Pituitary tumor transforming gene ( PTTG ), also known as securing, is a novel oncogene that is expressed at high levels in most of the tumors analyzed to date. Overexpression of PTTG in mouse fibroblast(NIH 3T3) cells increases cell proliferation,...
Integrins are major receptors for cell adhesion to the extracellular matrix, and play key roles in various cellular processes including adhesion, migration, proliferation and survival. Apart from developmental and physiological events, integrins...
This dissertation is a hypothesis-driven research oriented study to determine the role of the pituitary-tumor transforming gene (PTTG) in ovarian cancer, specifically if it is involved in neoplastic transformation leading to tumorigenesis through...
This thesis is an examination and analysis of the role of law enforcement in the transformation of a city's downtown from one dominated by sleazy strip bars and prostitutes to one of family entertainment. The focus is on the police and prosecutors;...
This thesis is an investigation into the world of sixteenth-century Venice, encompassing a group of female portraits by artist Palma Vecchio. I utilized many primary and secondary sources concerning Renaissance society, including several which...
Child molesters; Child sexual abuse--Research; Child sexual abuse--Diagnosis
An exploratory cross national study was conducted to determine if factors identified in the existing literature predictive for CSA in developed countries were also valid and predictive CSA factors for females in Belize, a developing country. The...
Temple of Zeus (Olympia, Greece); Sculpture, Greek--Greece; Olympia (Greece : Ancient sanctuary)
Built during the Early Classical period, the Temple of Zeus at Olympia and its sculptural program presented many new ideas in Greek society. I will argue that the Temple, in particular its metopes depicting the twelve Labors of Herakles,...
Epithelial Ovarian cancer (EOC) is the leading cause of gynecological cancer death in the USA. Recurrence rates are high after front-line platinum chemotherapy and most patients eventually die from platinum-resistant disease. P53 plays an important...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Paintings; Oil paintings; Locomotion; Human locomotion; Walking; Nudes; Stairways
"Marcel Duchamp submitted [to the 1913 New York Armory Show] Nude Descending a Staircase, No. 2, which was the most scandalous work of all. It was a humorous attack on Futurist proscriptions against traditional, Academic nudity. The image has...
"The vast majority of prehistoric sculptures depict either animals or humans. In the earliest art, humankind consists almost exclusively of women as opposed to men, and painters and sculptors almost invariably showed them nude […]. When...
c-Myc dysregulation is one of the most common abnormalities found in human cancer. MicroRNAs (miRNAs) are functionally intertwined with the c-Myc network as multiple miRNAs are regulated by c-Myc, while others directly suppress c-Myc expression. In...
Feminism in art; Art, Mexican; Women in art; Art and society--Mexico
This dissertation outlines a theoretical model for contextualizing contemporary
women's art practice in Mexico within the profound socioeconomic and political events
that have taken place since 1968, characterized by the steady breakdown and...
This thesis focuses on twentieth-century poet Frank O'Hara and his relationship to painting and painters in New York in the 1950s. An examination of the concept of ekphrasis functions as a theoretical frame and substantiation for the discussion of...
This thesis chronicles my journey within the framework of a hero's journey, as a theatre artist in the Master of Fine Arts program at the University of Louisville's Theatre Arts Department. This thesis is divided into six chapters that explore the...
In fulfillment of the thesis project requirement for the Master of Fine Arts Degree at the University of Louisville, I portrayed the multiple roles of Clytemnestra, Electra and Athena in Dr. Steve Schultz's translation of Aeschylus'...
Catalog of an exhibition of polacolor photographs by Henry Chodkowski presented by the University of Louisville, Allen R. Hite Art Institute, November 21, 1968-January 6, 1969.
