Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
This thesis reports the reactivity of the trithiolato Ru complex PPN[Ru(DPPBT)3] (DPPBT = 2-diphenylphosphinobenzenethiolate) (1a) with alkenes upon oxidation. Complex 1a in acetonitrile shows two redox events at -345 mV and +455 mV in the square...
Acting; Shakespeare, William, 1564-1616--Characters--Richard III; Shakespeare, William, 1564-1616. King Richard III
This thesis is a culmination of process and real life experiences I used as an actor to reach the goal of performing the role of Shakespeare's Richard III. Not only do I discuss the process I used, but I discuss the choices I made in pursuing this...
Nitrile hydratase (NHase) is a metalloenzyme that contains a non-heme iron (III)
or non-corin cobalt (III) in a non-redox active role. NHase is used as biocatalyst in the
industry for the hydrolysis of nitriles to arnides. The trivalent metal ions...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Image processing; Computer vision; Pattern recognition systems
Image segmentation is one of the most important problems in image processing, object recognition, computer vision, medical imaging, etc. In general, the objective of the segmentation is to partition the image into the meaningful areas using the...
Our research activities are based on the catalytic systems that provide resource-saving synthetic methodologies through gold-catalyzed reactions of alkynes and alkenes. We have worked on three applications: i) an effective and straightforward...
Chapter 1 detailed the synthesis method of hydroxamate peptides derivatives of pentapeptide Ac-PHSXX\'-N-NH2 by solid phase hydroxamate peptide synthesis method. The glutamic acid/aspartic acid side chain was modified to hydroxamic acid by on resin...
A careful perusal of Shakespeare’s works leads to one outstanding conclusion. Shakespeare was preeminently interested in words, as such. His every play shows a painstaking attention to words in their various shades of meaning. It is our interest...
This thesis reports the reactivity of the rhenium-thiolate complex, tris(2-diphenylphosphinobenzenethiolato)rhenium(III), [Re(DPPBT) 3 ] ( 1 ) and its oxidized derivatives with ethylene. The reactivity has been studied by electrochemical,...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Acting; Shakespeare, William, 1564-1616--Characters--Queen Margaret; Shakespeare, William, 1564-1616. King Richard III
This thesis is a brief examination of what is required to create a successful performance onstage, where a successful performance is defined by the audiences understanding of the text through the actor's performance. With that understanding comes a...
The purpose of the present study was to examine the relationship among organizational justice components, overall job satisfaction, and organizational commitment within the intercollegiate athletics setting. Perceptions of three organizational...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
The dental pathogen A. actinomycetemcomitans, a Gram- negative organism, has been associated with aggressive forms of periodontitis. A. actinomycetemcomitans requires iron to grow. In the host, iron-binding proteins such as transferrin,...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
The main purpose of this research is to make a comparative study of the physical mechanisms related to highway noise barrier insertion loss and to evaluate and improve the accuracy of insertion loss of FHWA Traffic Noise Model (TNM) 2.5 comparedw...
Background . Heart failure treatment guidelines emphasize the importance of daily weight monitoring. To support this practice, the Health Care Financing Administration Heart Failure Demonstration Project (2000) was designed to evaluate the effect...
The advent of larger storage spaces, affordable digital capturing devices, and an ever growing online community dedicated to sharing images has created a great need for efficient analysis methods. In fact, analyzing images for the purpose of...
