INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
Ligaments--Wounds and injuries; Knee--Wounds and injuries; Women athletes--Wounds and injuries
Anterior Cruciate Ligament (ACL) injuries are among the most common injuries incurred by both recreational and professional athletes. ACL injuries often occur during popular contact sports like basketball, football, volleyball and baseball, and...
Historically in the area of pediatric heart failure, few options have been available that are specifically designed to provide pediatric circulatory support. Extracorporeal Membrane Oxygenation (ECMO) was the traditional method of choice, providing...
Aortic Valve Bypass surgery has found renewed interest to researchers due to its application in high-risk patients with severe aortic stenosis. This therapy consists of construction of a conduit containing a bioprosthetic or mechanical valve from...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
Cardiology--Research--Methodology; Microfluidics--Equipment and supplies
Cardiovascular disease (CVD) is the leading cause of death in the United States and accounts for nearly 1,372,000 deaths each year. In addition, ~81 million Americans suffer from some form of CVD. Understanding the molecular basis of various...
CDCIWHO only "recommends" that rings be removed under gloves because of cross-contamination between health care workers and patients. Microbiological samples of oral streptococci beneath rings and between fingers under non-sterile exam...
A combination of three techniques – high resolution micro computed tomography (micro CT) scanning, Archimedes-based volume fraction measurement and serial sectioning or milling – were used to determine the volume fraction, trabecular thickness,...
Previous research has indicated the important role of visual information in the speech perception process. These studies have elucidated the areas of the brain involved in the processing of audiovisual stimuli. The McGurk effect, an audiovisual...
Heart--Diseases--Diagnosis; Diagnostic imaging; Magnetic resonance imaging; Imaging systems in medicine
Many cardiac diseases, such as myocardial ischemia, secondary to coronary artery disease, may be identified and localized through the analysis of cardiac deformations. Early efforts for quantifying ventricular wall motion used surgical implantation...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Neuropsychology; Motor ability; Eye-hand coordination
Two major theoretical models, Direct Mapping and Functional Equivalence, suggest that the observation of action and imagery of action, respectively, involve activation of similar motor related areas. Despite the wealth of evidence that supports...
Not many analyses of chylous fluids have been published. The analyses reported here were accordingly undertaken when a somewhat unusual opportunity for obtaining chylous fluid presented itself, with the object of adding to the data already...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
O -linked β-N-acetylglucosamine ( O -GlcNAc) is an inducible, dynamically cycling, and reversible post-translational modification of serine/threonine amino acid residues of nucleocytoplasmic and mitochondrial proteins. O -GlcNAc transferase (OGT)...
Electroencephalography; Visual evoked response; Drug addicts--Research
In 2006 it was estimated by the Substance Abuse and Mental Health Service Administration (SAMHSA, 2007) that 19.9 million Americans used illicit drugs, computing to roughly 8.0 % of the United States population. In 2007, there were 2.1 million...
Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all...
Background . Heart failure treatment guidelines emphasize the importance of daily weight monitoring. To support this practice, the Health Care Financing Administration Heart Failure Demonstration Project (2000) was designed to evaluate the effect...
Electroactive polymers (EAPs), including conducting polymers (CPs) such as polyaniline (PAn), and hydrogels are exciting areas of research in disciplines such as biomedical engineering, with the goal of creating low-cost, lightweight, non-toxic...
African Americans; African American physicians; African Americans--Hospitals; African Americans--Social conditions; African Americans--Education; Segregation in education; African Americans--Medical care; Hospitals; Medical education; Race...
Oral history interview with Louisville physician Maurice Rabb. Dr. Rabb discusses his early life and education in Mississippi. He speaks of his experiences as a student at Fisk University in Nashville, Tennessee, comparing race relations in his...
