The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Within the Appalachian hills of eastern Kentucky, large-scale coal mining operations are directly altering the headwater landscape through the construction of hollow fills. These man-made landforms and their associated in-stream structures alter a...
We are more likely to "hurt the one's we love" than we are complete strangers (cf. R. Miller, 1991, 1997). Early in dating relationships, partners appear to me more likely to manage their impressions to present themselves as better than...
African American students--Education; Mathematics--Study and teaching (Elementary); Academic achievement--Psychological aspects; Stereotypes (Social psychology)
African American students continue to underperform and are underrepresented in areas, including mathematics (Heubert & Hauser, 1999; Jencks & Phillips, 1998; National Postsecondary Education Cooperative, Gandara, Bial, & Educational...
Senile dementia; Nursing home patients--Mental health; Anxiety in old age; Depression in old age
Dementia, depression, and anxiety are the most common psychiatric disorders among long-term care residents and, because dementia is associated with behavioral problems that can be difficult to manage, the growing number of long-term care residents...
Professional ethics does not differ in its essential nature from general ethics; both are concerned with problems of human conduct. The difference between the two is a difference of scope but not of nature. The scope of general ethics is as broad...
Older people--Mental health; Philosophy of mind; Cognitive science--Health aspects
Declines in social resources and in the quality of interpersonal interactions have been observed in some older adults. Unawareness of ability is a clinical problem that has been found in some older adults with dementia, but has also been found in...
Computer music; Sound--Recording and reproducing--Digital techniques; Music and technology; Computer sound processing
This thesis proposes a concept called low-time-resolution (LTR) structure in music, and investigates its potential significance and application in music-related computing tasks.
The contributions of the thesis are manifold. First, it proposes a...
Income distribution; Occupational training--Economic aspects; Academic achievement--Economic aspects
Employing a two-stage least-squares multiple regression technique using cross-sectional data from metropolitan statistical areas (MSAs) as the unit of analysis, this study is designed to detect the indirect effect of skill-biased technological...
Inflammatory Bowel Disease (IBD) is a chronic illness with the potential to affect many areas of one's life through painful physical symptoms and psychological distress. Despite the debilitating nature and increasing prevalence of IBD, there is...
Capital punishment--Public opinion; Murder victims' families--Attitudes; Murder victims' families--Psychology
Two common assumptions are that the family members of murder victims will achieve closure and perceive a sense of justice following the execution of their loved one's murderer. These assumptions, however, may be unfounded. Using family member...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
An individual's role set consists of a variety of different roles (Biddle, 1979; Madsen & Hammond, 2005). Parent, spouse, student, and even sports fan, all constitute roles within one's role set. Fulfilling role demands requires time, energy,...
From a computerized image analysis prospective, early diagnosis of lung cancer involves detection of doubtful nodules and classification into different pathologies. The detection stage involves a detection approach, usually by template matching,...
Aquatic ecosystems face major transformations as humans increasingly alter their environment by introducing exotic species and changing the temperature regime and nutrient availability of freshwater systems. The impacts of such alterations of...
This study examined two questions related to interpersonal change as an outcome of Time-Limited Interpersonal Therapy (TLIPT). The first asked if clients experience both symptom change and interpersonal change when treated with TLIPT. The second...
This dissertation explores the physical and biological factors that control zooplankton population growth rates in the Ohio River (USA). I employed both observational studies and a mesocosm experiment to ascertain zooplankton population and...
Complement, an early recognition system of innate immunity that senses local tissue damage and infection, cross-talks with and regulates other signaling systems, including Toll-like receptor (TLR) pathways. In the context of periodontitis,...
College sports--Management; Athletic directors; Women college administrators; Women--Employment
The roles of assistant and associate athletic director have been identified as
positions in the "pipeline" to achieving the position of Athletic Director (Grappendorf,
Lough, & Griffin, 2004; Lapchick, 2010). Given the...
Child maltreatment touches almost 700,000 children annually. The effects
of child maltreatment range from micro-level consequences, such as behavior
problems and mental health issues, to mezzo-level consequences, such as
increased child...
