High-throughput sequencing has provided a myriad of genetic data for thousands of organisms. Computational analysis of one data type, expressed sequence tags (ESTs) yields insight into gene expression, alternative splicing, tissue specificity gene...
The past decade has brought about major advances in the realms of both
healthcare and biometrics. New technologies and techniques in the field of biometrics
has allowed for the quick and efficient identification of people, while new...
Age-related macular degeneration (ARMD) and retinitis pigmentosa (RP) are the two leading causes of blindness in the world today. Despite enormous efforts and advances in clinical treatment of eye diseases, there is no established method or cure of...
Activity-based rehabilitation is important for clinically treating spinal cord injury (SCI). Advances in SCI research are dependent on quality animal models, which rely on our ability to detect functional differences in animals following injury....
Neuropsychology; Motor ability; Eye-hand coordination
Two major theoretical models, Direct Mapping and Functional Equivalence, suggest that the observation of action and imagery of action, respectively, involve activation of similar motor related areas. Despite the wealth of evidence that supports...
Recent advances in high throughput methodologies offer researchers the ability to understand complex systems via high dimensional and multi-relational data. One example is the realm of molecular biology where disparate data (such as gene sequence,...
The facility layout problem is a combinatorial optimization problem that involves determining the location and shape of various departments within a facility based on inter-department volume and distance measures. An optimal solution to the problem...
Recent advances in understanding the molecular mechanisms of mutagenesis indicate that most mutations are dependent on the activity of translesion synthesis DNA polymerases. The impact of reducing the level of these polymerases on mutagenesis and...