The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Ischemic heart disease is the leading cause of mortality and morbidity in Western societies. Thus, understanding the molecular mechanisms to reduce myocardial ischemia and limit infarction size are of great importance. Ample evidence has shown that...
Oxidative stress-induced immunosuppression could be due to a decrease in CD4 + T lymphocyte activation or proliferation. 4-Hydroxynonenal (HNE), an end product of lipid peroxidation, and its protein adducts act as markers of oxidative stress. In...
Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Caption information: Kniender weiblicher Akt in gekauerter Stellung [Kneeling female nude in crouching position] / um 1917 [c. 1917]/ Studie zu “Leda” [Study of “Leda”] / Bleistift [pencil] / u. r.: Nachlassstempel [lower right: estate...
Caption information: Stehender weiblicher Akt nach rechts [Standing female nude seen facing right] / um 1915 [c. 1915] / Bleistift [pencil] / sig.: u. r. Gustav Klimt [signature: lower right Gustav Klimt] / Graphische Sammlung Albertina, Wien...