Activity-based rehabilitation is important for clinically treating spinal cord injury (SCI). Advances in SCI research are dependent on quality animal models, which rely on our ability to detect functional differences in animals following injury....
Spinal cord--Wounds and injuries--Treatment; Physical therapy
Activity-based rehabilitation in the form of overground or body weight-supported treadmill (BWST) locomotor step training has become the most widely accepted therapy translated from preclinical animal research to spinal cord injury (SCI) patients....
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
Human-animal relationships in literature; Coetzee, J. M., 1940---Criticism and interpretation; Coetzee, J. M., 1940---Characters--Elizabeth Costello; Animals (Philosophy); Animal rights
For the past four decades, scholarship on the relationship between human and
nonhuman animals has been growing inside the academy and sprouting ontological and
epistemological concerns about the status of the Humanities as an institution....
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughout life. Methods to isolate and expand the hONPs have been developed in our laboratory. In response to morphogens, the hONPs...
The goals of this dissertation is to further the understanding of the roles of two genes identified by differential display polymerase chain reaction (ddPCR) of cat visual cortex as candidate genes to play a role in visual cortical plasticity....
It is not the primary purpose of this present work to treat the problem of the evolution of behavior, but rather to give an analysis of animal behavior as observed. These observations may appear as simple tests, but they make possible a new way to...
Introduction: Hyperhomocysteinemia (HHcy) is a pathological condition characterized by excessive levels of plasma homocysteine (Hcy). Patients with HHcy are reported to be at risk for arrhythmias like atrial fibrillation and sudden cardiac death...
Background. Progression of alcoholic liver disease (ALD) is associated with an increase in fibrin extracellular matrix (ECM) and inflammation. Previous studies have shown that this accumulation of fibrin in ALD is mediated by impaired fibrinolysis....
Gene therapy; Spinal cord--Wounds and injuries; Tissue engineering
The combination of viral mediated gene delivery, tissue engineering, and Schwann cell (SC) transplantation offer a promising strategy to enhance axonal regeneration and functional recovery following spinal cord injury (SCI). The rationale and...
Griffithsin (GRFT) is a carbohydrate binding protein derived from the red alga Griffithisia sp. that has been shown to effectively interfere with the cellular attachment and infectivity of a number of viruses, including HIV-1. However, it is...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
Sensory neurons; Spinal cord--Wounds and injuries--Research; Pain--Research
This study examined the effects of tissue damage and inflammation on the expression in sensory neurons of P2X3, a gene that has a role in nociception and sensing bladder distension, which is regulated by nerve injury. Tissue damage induces...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
It is to be noticed that if there be any marshy places, certain animals breed there, which are invisible to the eye and yet getting into the system through the mouth and nostrils cause serious disorders." This quaint observation is taken from...
"Fate of the Beasts (1913), perhaps also related to the prevailing apprehensions of war, portrays a total, inescapable catastrophe. Hard, arrowlike diagonals intersect to shoot across the canvas. Trees bleed and descend in a cosmic cataclysm....
Osteoporosis has become a growing health threat with rising social and economic consequences. The understanding of the relationship between bone mechanical strength and bone structural quality is important for the diagnosis of osteoporosis and the...
Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is known to confer antioxidant protection in vivo. Rather than directly reacting with free radicals, however, SFN works by inducing Nrf2, a transcription factor that binds to...
"From the 'King's Grave' at Ur comes a splendid lyre that, in its restored state, resembles the instrument depicted in the feast scene on the Standard of Ur [from Tomb 779]. A magnificent bull's head caps the instrument's sound box. It is...
“Scenes from the Zliten mosaic showing (top left) a man condemned to be killed by beasts. He is pushed towards the animals on a miniature chariot. The other scenes show animals being hunted by venatores, and a fight between a bear and a bull...
