Age-related macular degeneration (ARMD) and retinitis pigmentosa (RP) are the two leading causes of blindness in the world today. Despite enormous efforts and advances in clinical treatment of eye diseases, there is no established method or cure of...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Computer arithmetic; Computer arithmetic and logic units; Computer algorithms
This research evaluates an innovative binary adder design and compares it against five standard adder designs. It begins with an algorithmic description of the five standard designs followed by the innovative design. It uses two metrics, speed and...
Wind power has the potential to provide access to electricity to areas lacking the resources to create industrial power plants, as well as supplement residential energy supplies. The low resource investment and ease of installation make it ideal...
Prints--Kentucky--Louisville--Exhibitions; Painting--Kentucky--Louisville--Exhibitions; Art quilts; Block designs; Screen process printing; Feminism and art
This thesis explores pattern juxtaposition using traditional American quilt block designs as the compositional basis for nine works pieced from screen printed paper. In the 1970s, the quilt was celebrated for its apparent connection to Modernist...
Over the last 15 years, researchers have explored the use of piezoresistive microcantilevers/resonators as gas sensors because of their relative ease in fabrication, low production cost, and their ability to detect changes in mass or surface stress...
Wheelchairs--Design and construction; Dogs--Equipment and supplies; Dogs--Health; Veterinary physical therapy
Hind limb paralysis may occur in dogs for a variety of neurological or musculoskeletal reasons. For dogs with limited mobility their lack of ability to ambulate can have a great impact on their physical and mental health. Canine wheelchairs can...
Air void structure in hardened concrete is critical to its durability. This project mainly focuses on investigating the air void system in hardened concrete with the microscopic analysis Linear Traverse Method specified by ASTM Specification...
Children's literature in mathematics education; Mathematics--Study and teaching (Elementary); Problem youth--Education (Elementary); Mathematics--Remedial teaching
Nationally, there are increasing numbers of students who are at-risk for academic and/or social failure (U.S. Department of Education, 2009). In an attempt to address this trend, the 2004 reauthorization of the Individuals with Disabilities...
In this dissertation, we study the performance evaluation of two automated warehouse material handling (MH) technologies - automated storage/retrieval system (AS/RS) and autonomous vehicle storage/retrieval system (AVS/RS). AS/RS is a traditional...
In this work, micro fabrication techniques are explored not only to simplify the production of complex lab on-a-chip devices (LOC), but also micro fabrication will be utilized to create intelligent design features that will enhance an...
Parks, Suzan-Lori. In the blood; Theaters--Stage-setting and scenery
From the moment the audience enters the auditorium the play is a mystery. They are looking for clues as to the nature of the story in which they are about to participate. The designer's job is to select what these clues are. How does the designer...
The thesis focuses on improving the flowrate of the Knudsen gas pump. The Knudsen pump uses thermal transpiration as the driving mechanism to pump gas. It is a motionless gas pump as the pump does not require any moving actuators for pumping. The...
In order to satisfy customer expectations, a ground vehicle must be designed to meet a broad range of performance requirements. A satisfactory vehicle design process implements a set of requirements reflecting necessary, but perhaps not sufficient...
The Knudsen pump works on the principle of thermal transpiration. As a result of requiring a thermal gradient, channel hydraulic diameter smaller than the mean free path of the gas being pumped, and having no moving parts, the Knudsen pump features...
Athletic cleated shoe failures are commonplace to competitive-level ultimate
frisbee players. Currently, there are no athletic cleated shoes designed for the sport of
ultimate frisbee; players generally choose between football or soccer cleated...
Wind energy provides an attractive power source as an alternative to fossil fuels because it is abundant, clean, and produces no harmful emissions. To extract more energy from the wind we need to increase the wind turbine size. However, the...
Microelectromechanical systems; Pumping machinery; Drug infusion pumps
Dermal wounds, including bed sores, pressure ulcers, and diabetic ulcers have a large impact on American healthcare costing up to $7 billion per year. Adequate pharmaceutical remedies applied at constant rate could prove to increase the healing...
The process of designing the settings and lighting for a show is an adventure; it's a story that has the normal components of any good story, a beginning, middle and end. There is tension, conflict, climax and resolution. It contains characters who...
This dissertation presents an analytical investigation that examined the seismic performance of steel stud backed and Concrete Masonry Units (CMU) backed masonry veneer wall systems, under in and out - of - plane loads, in medium rise building...
