Channel modification has played a vital part in shaping the rivers and streams as
they are seen today. Channel modifications range from the construction of dams and levees
for flood control purposes to channelization of an existing meandering...
It has been shown that GSK3 β plays a critical role in the inflammation response by differentially regulating MyD88-dependent pro- and anti-inflammatory cytokines production in TLR4-stimulated innate immune cells. The work included in this...
T lymphopoiesis has been an intense focus of immunological research since the discovery of the major histocompatibility complex (MHC) and T cell mediated transplant rejection. Additionally, researchers have long appreciated the role of T cells, and...
Quorum sensing (Microbiology); Cellular signal transduction; Bacterial genetics
Quorum sensing in the oral pathogen Aggregatibacter actinomycetemcomitans is dependent upon the soluble signaling molecule AI-2, but it is not known how the initial detection of AI-2 is coupled to the downstream regulation of gene expression that...
Complement, an early recognition system of innate immunity that senses local tissue damage and infection, cross-talks with and regulates other signaling systems, including Toll-like receptor (TLR) pathways. In the context of periodontitis,...
Exocytosis of intracellular granules is critical for conversion of inactive, circulating neutrophils to fully activated cells. The p38 MAPK pathway plays a central role in neutrophil exocytosis, although its mechanism of action is unknown. We used...
Hemolysis, the major cause for specimen rejection in clinical laboratories is defined as the rupture of red blood cell membranes, resulting in the release of hemoglobin into the plasma. Blood flow in needles causes hemolysis resulting in...
A group of people and a couple of dogs on the bank of a stream. Two women are fishing in the foreground and several others are fishing further downstream. This group is apparently visiting the mineral springs in Cerulean Springs.
A group of black and white men and boys stand on the banks of a stream, separated from a row of houses with picket fences by a dirt road lined with utility poles. Downstream from the group there is a small bridge and more houses. Apparently this...
Old Salt River Bridge at Taylorsville, Kentucky, built in 1833, and replaced in 1933. A horse and carriage with two passengers drives from the bridge. A man dressed in white stands at the left, behind the carriage. At the right, a sign warns about...
Side wheelers; Steamboats; Launchings; Boat & ship industry; Howard Ship Yards and Dock Company
CITY OF LOUISVILLE, a side-wheel packet with wood hull (301 ft. x 42.7 ft. x 7 ft.), was built at Howard in 1894. Owned by Louisville & Cincinnati Packet Co., CITY OF LOUISVILLE operated on the Ohio River between Louisville and Cincinnati. She...
Stern wheelers; Tugboats; Steamboats; Launchings; Boat & ship industry; Howard Ship Yards and Dock Company
HELEN H., a stern-wheel towboat with a diesel engine and steel hull (85 ft. x 22 ft. x 4.3 ft.), was built at Howard in 1931. HELEN H. operated in the Louisville area. HELEN H. was bought by Amherst Barge Company in 1956 and renamed EMMA No.3.
Stern wheelers; Steamboats; Launchings; Boat & ship industry; Howard Ship Yards and Dock Company
BLUFF CITY, a stern-wheel packet with wood hull (225 ft. x 42 ft. x 6 ft.), was built at Howard in 1896. Owned by Anchor Line, she operated on the Mississippi River between St. Louis and New Orleans. BLUFF CITY was the last boat, and the only...
Ferries; Side wheelers; Steamboats; Boat & ship industry; Howard Ship Yards and Dock Company
CITY OF JEFFERSONVILLE, a side-wheel ferry with wood hull (150 ft. x 34 ft. x 6.3 ft.), was built at Howard in 1891. Owned by Louisville & Jeffersonville Ferry Co., she operated in the Louisville area until she was retired around 1914.
Stern wheelers; Tugboats; Steamboats; Howard Ship Yards and Dock Company
D.A.B., a stern-wheel towboat with steel hull (63 ft. x 16 ft. x 3.0 ft.), was built at Howard in 1921. Owned by Wheeling Steel Corporation, D.A.B. operated in the Pittsburgh area. She initially had a gas engine with a chain drive stern-wheel, but...
Stern wheelers; Tugboats; Steamboats; Boat & ship industry; Howard Ship Yards and Dock Company
NORTHERN, a stern-wheel towboat with wood hull (125 ft. x 26 ft. x 4 ft.), was built at Howard in 1908. Owned by E. T. Slider in Louisville, Kentucky, NORTHERN operated on the Ohio River near Louisville, towing sand and gravel. She was dismantled...
Stern wheelers; Tugboats; Steamboats; Boat & ship industry; Howard Ship Yards and Dock Company
DONORA, a stern-wheel towboat with steel hull (140 ft. x 32 ft. x 6 ft.), was built at Howard in 1924. Owned by American Steel & Wire Co., she operated on the Monongahela River until she was retired in 1948.
Stern wheelers; Steamboats; Boat & ship industry; Howard Ship Yards and Dock Company
WM. GARIG, a stern-wheel packet with wood hull (175 ft. x 35 ft. x 5.2 ft.), was built at Howard in 1904. Owned by Baton Rouge & Bayou Sara Packet Co., WM. GARIG operated on the lower Mississippi and Ouachita Rivers. In 1918, she was sold to...
Pier no. 1, span no. 1, half of span no. 2, the cliff face, and north tower as viewed from the riverbank downstream during construction of High Bridge over the Kentucky River. Two piers anchored in concrete support the three 375 foot spans of the...
