Heart failure is the most frequent cause of mortality in western countries. Currently, there is no cure treatment for heart failure and the long term survival rate following heart failure is poor, with one third of patients dying within a year of...
Interactions between chemokines and their receptors are involved in organ- specific homing and propagation of metastatic breast cancer (BrCa) cells. BrCa cells express higher levels of CXCR4 and CXCR7 mRNA and cell surface protein, than normal...
Williams syndrome--Genetic aspects; Anxiety disorders
Genetic factors play an important role in the etiology of anxiety disorders. Williams syndrome (WS), a genetic disorder caused by a deletion on chromosome 7q11.23 and associated with increased prevalence of anxiety disorders relative to the general...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
Fiber-reinforced polymer matrix composites (PMCs) using high-temperature thermoplastics as the matrix material represent a lightweight design solution for applications above 250°F. This is often required for aircraft structures subjected to...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
City & town life; Elevated railroads; Railroads; Pedestrians; People
Narrow city street with an elevated railroad to the right and buildings on either side. The sidewalk on the left is crowded with pedestrians. A train passes on the elevated railroad. Title: New York's great 'shopping' district and Elevated Railway,...
Train passing on elevated railroad tracks. A road runs below the tracks with carriages on it. Building are in the background. Title: 901 - Elevated Railroad (Eighth Avenue), New York, N.Y., U.S.A. Text on left: Keystone View Company, Manufactures...
City & town life; Elevated railroads; Street railroads; Railroads; Pedestrians; People
View of streets and elevated railroad tracks in New York City. Buildings line the streets on the right, while the railroad tracks run perpendicular to the streets. Carriages, streetcars, and pedestrians are on the streets. Trains run on the tracks....
Oxygen is critical to aerobic metabolism, but hyperoxia is cytostatic and cytocidal. The precise mechanisms involved in hyperoxic cell injury remain incompletely understood although there is substantial support for the possibility that hyperoxia...
Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Prostate--Cancer--Diagnosis--Cost effectiveness; Medical screening--Cost effectiveness
Prostate cancer is a common form of cancer in men. In fact, prostate cancer has the highest incidence of any cancer in men. Prostate cancer is not only common, it carries a significant financial burden. The cost of prostate cancer is 11.3% of all...
Polycyclic aromatic hydrocarbons; Fetus--Effect of tobacco on
Polycyclic aromatic hydrocarbons (PAH) are chemicals generated from the incomplete combustion of organic materials, including tobacco smoke. Some PAH are known to be mutagenic and carcinogenic in humans, and of concern for the fetus when women...
Curved portion of an elevated railroad with a train approaching the curve on the outside set of tracks. Ships are visible in the water in the background. Title: Elevated Railroad, Coenties Slip, New York, U.S.A. Text on bottom: Copyright, 1893, by...
View from the street of the elevated railroad above and to the left. A train is at the curve in the tracks. Buildings are in the background on either side of the elevated railroad. Pedestrians and carriages are on the street. Title: Highest Point,...
Elevated railroad station for an elevated railroad. A small building with windows and covered stairs leading from the ground. A group of people stand in front of the stairs. Title: N.Y. Elevated R.R., N.Y. Text on left and right: American Series.
Train cars on elevated railroad tracks over a city street in New York. Pedestrians walk on the sidewalk below the tracks. Title: 15094 Elevated R. R. at 4th Ave., New York. Text on left: American and Foreign Views. Text on right: Sold only by...
View from the tracks of an elevated train on the railroad tracks above city streets. Buildings are on either side. Pedestrians and carriages are on the street below. Title: 2002 New York, Elevated R. R. and Chatham Square. Text on left: Sold only...
View from above of Herald Square in New York City. Multiple buildings can be seen along the streets. Below, there are pedestrians and streetcars. Railroad tracks run through the center. Smoke blows out from the trains on the tracks. Title: Herald...
View from the street of a train on elevated railroad tracks approaching a curve. On the street are carriages and wagons. Two people sit at the front of the wagon on the left. Title: 6495. Elevated Railway, South Ferry, New York, U.S.A. Text on...