MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
The mechanisms by which estrogens regulate mitochondrial activity are not completely understood. Chronic treatment of ovariectomized rats with estradiol (E 2 ) increased the amount of Nuclear Respiratory Factor-1 (NRF-1) protein in cerebral blood...
Women--Kentucky--Louisville; Social reformers--Kentucky--Louisville--History; Morel, Louise C., b. 1871
Louise C. Morel was a leading social reformer in Louisville from 1917 through the early 1940s. Morel's work is a primary example of the continuation of Progressive Era ideals into the decades after the traditional end of the Progressive Era....
The purpose of this dissertation is to suggest that peace is an idea that changes throughout the history of the west, rather than to show how nations may achieve peace or to define what it is. It begins as a concept the power brokers refer to or...
Jin, Ha, 1956-; Masculinity in literature; Chinese literature--20th century; Sex (Psychology) in literature
This dissertation consists of readings of three selected novels by Ha
Jin-Waiting, The Crazed, and A Free Life. These novels cover three historical
periods of Contemporary China under the rule of the Communist Party in
sequence-the Mao's era...
Kentucky--History--1792-1865; United States--History--Civil War, 1861-1865--Causes
During the secession winter of 1860-61 the Commonwealth of Kentucky found itself caught in the middle of the great sectional controversy. With the Union's fate hanging in the balance Kentucky figured as a prominent player in the outcome of that...
Slavery--Political aspects--Kentucky; Kentucky--History--Civil War, 1861-1865
In his 1926 study of the Civil War era in Kentucky, southern historian E. Merton Coulter repeated the old saying that Kentucky was the only state to secede after Appomattox. In an over-simplification of the process, most historians have seen harsh...
Cumberland Falls State Park (Ky.); Historic preservation--Kentucky
This thesis is an examination of Louisville Times editor Tom Wallace's fight to prevent the construction of a hydroelectric dam at Cumberland Falls, Kentucky between 1926 and 1931. By mining Wallace's recently cataloged personal papers, this study...
This dissertation explores how presidential inaugural speeches reflect the overarching mindset of the government, and how, in the postmodern era, this mindset manifests the same sort of African American erasure that has existed since Middle...
This thesis is an exploration of Black cultural space and its influence on the
retention, adaptation, and transmission of African folktales during and after the
antebellum era. During slavery, the survival of kinship and family helped to create
an...
Children and war; World War, 1939-1945--Kentucky--Louisville; World War, 1939-1945--Indiana--Madison; Girls--Indiana--Madison; Girls--Kentucky--Louisville
This thesis presents the view of World War II, a watershed event in U.S. history, through the lenses of a group that is not normally called upon, that of young children. The war was viewed by and affected young girls differently than others....
Businesswomen--United States--History--20th century; Women, White--United States--History--20th century; Businesswomen--United States--Psychology; Women, White--United States--Psychology; Self-perception in women--United States
The purpose of this cross-disciplinary dissertation is to explore how the epistemic ruptures, such as WWII and the Second Wave Feminism, change the American society between 1963 and 1985. From a humanistic and historical point of view, it focuses...
St. Irene (Church : Istanbul, Turkey); Irene, Empress of the East, 752?-803; Constantine V Copronymus, Emperor of the East, 718-775; Apses (Architecture)--Turkey--Istanbul; Art patronage--Turkey--Istanbul--History--8th century
The mosaic of the cross in the apse of Hagia Eirene in Constantinople is examined in order to determine the imperial patron responsible for it's construction. Key points in this study are Orthodox image veneration, Iconoclast doctrine and the...
McLaughlin, Lennie, 1900-; Democratic Party (Ky.)--History; Louisville (Ky.)--Politics and government; Women--Political activity--Kentucky--Louisville
This thesis seeks to examine the role of the Democratic Party organization in Louisville, Kentucky and its influence in primary elections during the period 1933 to 1963. A prominent party leader, Lennie McLaughlin, is the focal point of the study....
Educational leadership--Kentucky; Educational accountability--Kentucky; Educational change--Kentucky; School improvement programs--Kentucky
In 1983 the National Commission on Excellence in Education released A Nation at Risk, which triggered an extended era of school reform culminating in today's accountability movement. In Kentucky the school improvement process, in which principals...
Liberty--Philosophy; Enlightenment--France; Désert de Retz (Chambourcy, France); Gardens, English--France--Chambourcy
Freedom is a critical concept that helps shape the discourse of modern society and corresponding thoughts about people's private, public, cultural and spiritual lives. Standing at the fountainhead of the modern era, the Enlightenment was a critical...
Authors, South African--20th century; South Africa--In literature; Protest literature, South African (English); Mphahlele, Es'kia, 1919-2008. Down Second Avenue; Dikobe, Modikwe, 1913- Marabi dance; Mda, Zakes. Madonna of Excelsior; Mhlongo,...
Through content analysis of Ezekiel Mphahlele's Down Second Avenue,
Modikwe Dikobe's The Marabi Dance, Zakes Mda's The Madonna of Excelsior,
and Niq Mhlongo's After Tears, this study compares the themes of pre- and post-
1994 South African township...
Federal aid to education; Student aid--United States; Education, Higher--United States
This thesis is a historical analysis of the role the federal government has had in the in development student aid funding in the modern public four-year higher education system. It begins with a historical overview of the rise of progressivism as a...
Drug resistance in microorganisms--Mathematical models; Intensive care units
Antibiotic resistance is a problem causing growing concern in the medical community, leading some to speculate that a return to the preantibiotic era is imminent. The problem of antibiotic resistance is particularly significant in the intensive...
Ford Motor Company; Business logistics--Management; Production management; Manufacturing processes; Organizational change
For many years the concept of Lean Manufacturing has been applied in automotive development as a tool to refine the manufacturing practices to the greatest efficiency possible through waste reduction. Continuous Improvement is a quality innovation...
