Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Pancreatic islet transplantation is a very promising treatment for type I diabetes. Many clinical trials have failed due to early islet loss and immune rejection. Reactive oxygen species (ROS) have been demonstrated to be involved in graft damage...
Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
This thesis is divided into two parts below. Part I Adriamycin (ADR) can produce nephrotoxicity in rodents. The underlying mechanism may relate to ADR induced oxidative stress. In this study, we used transgenic mice (NMT3), which over-expressed the...
Train descending elevated railroads on a steep mountainside. Title: Jacob's Ladder, Mt. Wasn'n [Mt. Washington] Railway, N.H. Descriptive information on back of card: Photographed and Published by S.F. Adams, New Bedford, Mass.
Train engine car and passenger car on a very steep set of railroad tracks. People stand in front of and behind the train, with more people visible inside the passenger car. 'Mt. Washington' can be read across the side of the train car. Title: 538....
Train engine car and passenger car on a very steep set of railroad tracks. Despite the caption, the train appears to be descending with the engine at the lower level. People stand in front of and behind the train, with more people visible inside...
Water spraying and cascading down a cluster of large stones in front of a portion of a wall or bridge. The P. & O. Railroad is the Portland & Ogdensburg Railroad. Text on left: J.W. & J.S. Moulton, Salem, Mass. Text on right: New...
Railroad tracks and wooden walkway on a mountain. There are trees to the left and rocks to the right. A number of men stand on the walkway. On the tracks is a small train car holding men and women. Title: No. 101. Rail Road on to Mt Washington....
Railroad tracks and a wooden bridge or support on a mountain. There is a railing visible at the base of the hill. Two men stand on the support. There are two small trains, two cars each, on the tracks holding men. Title: No. 682. Mt. Washington...
Two sets of railroad tracks on a mountain with a wooden support beneath. One set of tracks angles to the right and has a three-car train on it. People are visible through the windows of the back car. Title: 1812. Train leaving the Depot, Mt....
Elevated train tracks on a wooden support with criss-crossed beams in an 'S' shape on a mountain. A train with two cars appears to be descending the mountain. People are visible through the windows of the back car. Title: 183 Jacob's Ladder - Mt...
Man sits on a small contraption in the middle of a set of railroad tracks, descending a mountain. The man wears a cap and has his legs out in front of him. In the background, at the top of the mountain, people stand to the side of a tunnel. Title:...
Train descending a steep mountain across rocky land. Tall trees are in the background. People are visible inside the train cars and along the side of the bridge. Title: No. 104. Rail Road on to Mt. Washington. Descriptive information on back of...
Train descending a steep mountain on tracks elevated on wooden supports across the uneven land. There are two train cars, including the engine. People are visible in the rear car. Handwritten on back: Jacobs Ladder Mt Washington R.R. Kilburn #135.
Train, consisting of two cars, on a set of railroad tracks across a rocky terrain. Four men stand in front of the train. People are inside the rear car. Title: No. 538 Train on Mt. Washington Rail Road. Descriptive information on back of card:...
Two wooden buildings with carriages and wagons around them and trees in the background. The building on the right has three stories and multiple windows. The building on the left is smaller and has train cars and other items in front of it. Title:...
Title: No. 693 R.R. Trains on Mt. Washington. Train on a set of railroad tracks across a very rocky terrain. A building with a steep roof is in the background near the top of a hill. People sit on the rocks beside the train and in the passenger...
Small train at a wooden platform with a building to the left. People stand at the platform and on the ramp leading to it. More people are visible inside the rear train car and on the front car. The ground in front of the platform is rocky. Title:...
Small train descending on a set of elevated tracks supported by wooden beams across a steep landscape. The train is crowded with passengers visible through the windows and standing on the rear of the train. Title: 802. The wonder of the Age, Mt....
