The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is known to confer antioxidant protection in vivo. Rather than directly reacting with free radicals, however, SFN works by inducing Nrf2, a transcription factor that binds to...
4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are highly reactive á,â-unsaturated aldehydes. 4-HNE and acrolein are generated in vivo as products of lipid peroxidation. These aldehydes are implicated in the onset of several diseases...
