Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Pancreatic islet transplantation is a very promising treatment for type I diabetes. Many clinical trials have failed due to early islet loss and immune rejection. Reactive oxygen species (ROS) have been demonstrated to be involved in graft damage...
Pancreatic adenocarcinoma is the fourth leading cause of cancer death in the United States. It is identified by its rapid, invasive progression with a profound resistance to treatments such as chemotherapy. Unfortunately, there is a lack of...