Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
Green River Valley (Ky.)--History--19th century; Green River Valley (Ky.)--Economic conditions--19th century; Farms, Small--Kentucky--History
This study focuses on the expansion of the Green River's economic and political importance within Kentucky and how it impacted small farmers of the region. It challenges the idea that small farmers played an insignificant role in the agriculture...
Blood flow--Measurement; Spinal cord--Wounds and injuries
Traumatic injury destroys blood vessels at the injury epicenter and is followed by local
angiogenesis and regional inflammation. Healing from injury depends on vascular health because
blood supply is directly responsible for the health and function...
Osteoporosis has become a growing health threat with rising social and economic consequences. The understanding of the relationship between bone mechanical strength and bone structural quality is important for the diagnosis of osteoporosis and the...
Former Soviet republics--Politics and government; Youth movements--Former Soviet republics; Georgia (Republic)--Politics and government--1991-; Kyrgyzstan--Politics and government--1991-; Ukraine--Politics and government--1991-
In 1991, as democratic ideals spread through the former Soviet sphere, newly independent nations and satellite countries began engaging in the truly challenging, albeit hopeful task of dual state- and democracy-building endeavors. After twenty...
Channel modification has played a vital part in shaping the rivers and streams as
they are seen today. Channel modifications range from the construction of dams and levees
for flood control purposes to channelization of an existing meandering...
Outerplanar graphs are planar graphs that have a plane embedding in which each vertex lies on the boundary of the exterior region. An outerplanar graph is maximal outerplanar if the graph obtained by adding an edge is not outerplanar. Maximal...
This study is a historical analysis of reasons and dynamics behind the emergence of fundamentalist religious movements. Its purpose is to develop a new conceptual apparatus to the approach toward religious fundamentalist movements that would...
Computer-aided minimally invasive surgery (MIS) has progressed significantly in the last decade and it has great potential in surgical planning and operations. To limit the damage to nearby healthy tissue, accurate modeling is required of the...
This thesis is an economic and historical examination of Keeneland racetrack in Lexington, Kentucky. The material commences with a historical overview of the role of sport and recreational activities in the United States. Putting sport and leisure...
Municipal government--Japan--Case studies; Administrative agencies--Reorganization; Globalization--Political aspects; Globalization--Government policy; Globalization--Japan; Tokyo (Japan); Osaka (Japan)
This study examines the effects of globalization on state restructuring and the status of cities and local governments. I conduct a comparative case study of two Japanese world cities, Tokyo and Osaka, Japan. Existing globalization theories offer...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
Inflammatory bowel disease (IBD) is a chronic autoimmune disorder that is subdivided into Crohn's disease (CD), ulcerative colitis (UC), and indeterminate colitis (IC). Epidemiological studies have proven that genetic variation increases...
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most fatal, with a rising incidence in the US as a result of the increase in alcoholic liver disease and obesity. Current therapeutic strategies are...
The current status of our knowledge of synaptic plasticity comes largely from studies of the hippocampus and the context of learning and memory. We remain largely ignorant of plasticity in other neural systems and contexts. The molecular basis of...
Indians of North America--Kentucky--Bullitt County--Antiquities; Excavations (Archaeology)--Kentucky--Ashworth Rockshelter site; Ashworth Rockshelter site (Ky.)
Reinvestigation of a National Register property, the Ashworth Rockshelter (15BU236), northeast of Shepardsville, Bullitt Co., Kentucky, revealed stratified Early Archaic through Mississippian components (ca. 7900 B.C.-1500 A.D.). Primary occupation...
Coal-fired power plants--Environmental aspects--United States; Mercury wastes--Environmental aspects--United States
This dissertation tests whether or not mercury emissions from electric power plants are not a significant contributor to mercury measurements in rainfall and argues that the current United States (U.S.) Environmental Protection Agency (EPA)...
This thesis is a methodological analysis of fire locations in Canadian provinces
from 2001 to 2010. The research presented in this thesis highlights the dominant fire
types for each province. Accurately locating active fires and burned area is...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...