In the electronic and microfabrication industry, die separation is one of the most critical steps in producing an undamaged, stand-alone micro-scale device. For silicon based devices, it is the predominant step governing resistance to die failure...
Fiber-reinforced polymer matrix composites (PMCs) using high-temperature thermoplastics as the matrix material represent a lightweight design solution for applications above 250°F. This is often required for aircraft structures subjected to...
Hemolysis (red cells lysis) caused by fluid stresses in flows within hypodermic needles, blood pumps, artificial hearts and other cardiovascular devices, is one of the major concerns during the design and use of cardiovascular or blood-processing...
Athletic shoes; Foot--Wounds and injuries--Prevention
The purpose of this investigation was to determine if cycling shoes made with stiff material cause an increase in peak plantar stress over shoes with less stiff material. Shoe stiffness measurements were collected under controlled conditions and in...
Aluminum fiber metal laminates (AFMLs) are a promising new type of fiber metal laminate that consists of aluminum foils interleaved with layers of a graphite fiber-polymer matrix composite (PMC) material. AFMLs combine the attractive features of...
Intimate partner violence--Psychological aspects; Victims of family violence--Rehabilitation; Victims of violent crimes--Mental health; Creative writing--Therapeutic use; Post-traumatic stress disorder--Treatment
Described as important long-term consequences of trauma exposure, disruptions in emotional processes are regarded as central features of posttraumatic stress disorder (PTSD); however, the nature of these posttraumatic emotional disruptions remains...
Women refugees; Women immigrants; Women--Violence against; Stress management for women
An interest in privileging the voices of women who are marginalized in many parts of the world coupled with knowledge of the restorative properties of music cultivated this qualitative study. Seven women, ages 20-49 years of age, from three...
This work presents a novel comprehensive effort to understand the fluid dynamics within orbiting dishes and the effects of the resulting oscillating fluid flow on shear and endothelial cellular responses within the dishes. It is well documented...
Wheelchairs--Design and construction; Dogs--Equipment and supplies; Dogs--Health; Veterinary physical therapy
Hind limb paralysis may occur in dogs for a variety of neurological or musculoskeletal reasons. For dogs with limited mobility their lack of ability to ambulate can have a great impact on their physical and mental health. Canine wheelchairs can...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Hypoxia is characterized by an inadequate oxygen supply to the tissues in
proportion to their metabolic needs, and is a primary factor in traumatic CNS
injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The
cAMP-dependent...
O -linked β-N-acetylglucosamine ( O -GlcNAc) is an inducible, dynamically cycling, and reversible post-translational modification of serine/threonine amino acid residues of nucleocytoplasmic and mitochondrial proteins. O -GlcNAc transferase (OGT)...
Prostate cancer (PCA) development may be influenced by genetic variations within oxidative stress response (OSR) related mechanisms, such as antioxidation (e.g.,
carcinogen metabolism/detoxification), DNA repair, and apoptotic regulation. Excessive...
Myocardial infarction; Glucose--Metabolism; Mitochondrial DNA
Heart failure is a leading cause of morbidity and mortality in the USA. During the development of heart failure, many cardiac parameters change at the same time including fuel metabolism, oxidative stress and mitochondrial function. Each of these...
In July 1995, National Science Foundation Award # 9551869 funded the development of a new inter-disciplinary microfabrication course under the primary leadership of Dr. Kevin Walsh at the University of Louisville. Along with this award, the...
Bi-stable buckled MEMS (micro-electromechanical systems) diaphragms have a myriad of uses in the MEMS field for their large out-of-plane deflections. Buckling is a phenomenon brought upon by a compressive stress. Diaphragms are large aspect ratio,...
Graft rejection; Diagnostic imaging; Postoperative care
The fourth hand transplant recipient in Louisville lost his graft at nine months post transplant from ischemia due to severe graft arteriopathy. Conventional imaging techniques and clinical measurements, including CT angiography and measurements of...
Welfare recipients--United States; College students--United States
Using Schlossberg's transition theory as the conceptual framework, this case study explored and identified the coping strategies used by seven welfare recipients attending postsecondary institutions. Three participants were enrolled in the local...
Oxidative stress-induced immunosuppression could be due to a decrease in CD4 + T lymphocyte activation or proliferation. 4-Hydroxynonenal (HNE), an end product of lipid peroxidation, and its protein adducts act as markers of oxidative stress. In...
