In blood coagulation, the serine protease thrombin is a multifaceted enzyme that interacts with multiple proteins. Thrombin utilizes two anion binding exosites (ABE-I and II) to supplement binding to fibrinogen and to the platelet receptor GpIbα,...
The Combinatorial Nullstellensatz can be used to solve certain problems in combinatorics. However, one of the major complications in using the Combinatorial Nullstellensatz is ensuring that there exists a nonzero monomial. This dissertation looks...
This dissertation describes new procedures for synthesizing and purifying Au and Au/Ag nanoplates directly on surfaces as well as controlled binding of proteins to their surface. It also describes fundamental changes in the optical properties of Au...
A connected matching in a graph is a set of disjoint edges such that, for any pair of these edges, there is another edge of the graph incident to both of them. This dissertation investigates two problems related to finding large connected matchings...
BACKGROUND: Regulated secretion of protein by salivary and other exocrine glands requires correct trafficking of soluble cargo proteins into secretory vesicles. However, the molecular mechanism of sorting in the parotid salivary gland is unknown....
The mechanisms by which estrogens regulate mitochondrial activity are not completely understood. Chronic treatment of ovariectomized rats with estradiol (E 2 ) increased the amount of Nuclear Respiratory Factor-1 (NRF-1) protein in cerebral blood...
Indians of North America--British Columbia; Literacy--British Columbia--Case studies
This dissertation examines the literacy practices of a group of First Nations women who live in British Columbia and whose jobs entail the production and dissemination of texts which reflect the local, Carrier, culture. In this qualitative study of...
Shakespeare, William, 1564-1616; Great Britain--History--16th century; Great Britain--History--17th century
Of all the arts drama is the most democratic. Other forms of artistic and aesthetic expression, literature, music, painting, may be cultivated in solitude. Not so the drama. It is demanded by the public; produced for the public and unless it is...
Learning and scholarship--Outlines, syllabi, etc.; English language--Rhetoric-- Outlines, syllabi, etc.; Education, Higher--Curricula; Instructional systems--Design
This dissertation is an investigation of composition's disciplinary conceptions of the course syllabus, from its often-relegated position as textual object to a more interactive and complex subject of our discipline. The course syllabus is an...
A group stands on a cobblestone road. A little boy wearing bib overalls and a straw hat holds a sign reading "Derby Bound." Next to him is a toddler in a small two-wheeled wagon that is strapped to a dog. Behind them is a man in a woman's...
Big Four Bridge; Bridges; Railroad bridges; Men; People; Transportation
A man stands at the Louisville side of the Big Four Bridge as a train crosses the Ohio River. The train is Interstate Public Service Co #208, bound for Indianapolis. Along the left section of the bridge is a pedestrian walkway while the center of...
John P. Grieb of Louisville, Kentucky posing beside newly bound books and a pile of books that are falling apart. The photograph has been painted on and marked with discoloration. Handwritten on back of image: John P. Grieb, Headed Grieb Printing...
Jean Thomas, holding two bags, and Jilson Setters (a pseudonym for James William (J.W.) Day, 1860-1942), holding two bags and a basket with his drinking gourd, stand on the deck of a ship bound for England. Jean Thomas selected Setters to represent...
Jean Thomas, followed by her sister Trixy Bell, walks down the steps between decks on the ship bound for England, where they will be attending the Festival of the English Folk Song and Dance Society held in Royal Albert Hall in London, England....
Trixy Bell, sister of Jean Thomas, looks out from the deck of a ship bound for England, where she will be attending the Festival of the English Folk Song and Dance Society held in Royal Albert Hall in London, England. Title supplied by cataloger.
Jean Thomas (right) and her sister, Trixy Lydia Ross Bell (left), wearing coats and hats, stand on the deck of the ship bound for England, where they will be attending the Festival of the English Folk Song and Dance Society held in Royal Albert...
Group portraits; Opera singers; Men; Women; Ships; Ocean travel
Group portrait of five men and two women, from the company of "Trilby," a three-act comic play, aboard a steamer bound for Australia. The men, standing, wear hats or caps with suits and ties, and the women, seated, wear blouses with puffy...
Maps; Floods; Disasters; Floods--Kentucky--Louisville--1920--1940; Floods--Kentucky--Louisville; Floods--Ohio River
Map showing, in blue, the areas of Louisville, Kentucky, affected by the 1937 flooding of the Ohio River. Includes Street Index on recto, and description of the flood, chart of elevations of the Ohio River during floods dating back to 1832,...
Stacks of a harvested agricultural product are covered with snow. The product is probably hemp which was retted outdoors before being bound and shipped to plants where it was spun into twine and rope. Hemp was Kentucky's largest cash crop until...
Sunrise or sunset over a farm field in winter. The stacks in the field could be corn, but are probably hemp. After hemp was cut, it was retted outdoors before being bound and shipped to plants where it was spun into twine and rope. Hemp was...
