The purpose of this study was to assess the effects of short-term high-intensity resistance training on time to exhaustion at maximal aerobic output. It was hypothesized that 2 weeks of training will induce improvements in performance at maximal...
Drug resistance in microorganisms--Mathematical models; Intensive care units
Antibiotic resistance is a problem causing growing concern in the medical community, leading some to speculate that a return to the preantibiotic era is imminent. The problem of antibiotic resistance is particularly significant in the intensive...
Writing centers; English language--Rhetoric--Study and teaching (Higher); Tutors and tutoring
Using Gloria Anzuldula's text Borderlands/La Frontera: The New Mestiza and Bruce Homer and Min-Zhan Lu's 2000 article, "Expectations, Interpretations and Contributions of Basic Writing" as conceptual framework, I conducted my dissertation...
Identity (Philosophical concept) in art; Museum techniques; Museum exhibits--Social aspects; Museums--Social aspects
This thesis paper expands upon the aspects of identity and power explored in the exhibition that I curated, entitled "Being & Making: Artists Investigating Identity," at the Speed Art Museum. The developments on topics of identity...
Gene therapy; Spinal cord--Wounds and injuries; Tissue engineering
The combination of viral mediated gene delivery, tissue engineering, and Schwann cell (SC) transplantation offer a promising strategy to enhance axonal regeneration and functional recovery following spinal cord injury (SCI). The rationale and...
Research--Moral and ethical aspects; Sociology--Research--Moral and ethical aspects
This dissertation is a comparative theoretical analysis of human rights, research ethics and human subjects protection. The history of human rights is a long one, but for the sake of immediacy and focus, the author will limit the discussion to...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
The fundamental question of the exact nature of the role played by TNF in the failing myocardium remains one of contention. Many preclinical studies have demonstrated beneficial effects with TNF antagonism and recently the dichotomous role played...
Sierra Leone--History--Civil War, 1991-2002--Causes; Sierra Leone--Social conditions; Postwar reconstruction--Sierra Leone
This multilayered study is an appraisal of some of the ongoing post-conflict reconstruction efforts in Sierra Leone in light of the causes of the conflict, which lasted from 1991-2002. It begins by providing a critical examination of the historical...
Longitudinal studies occupy an important role in scientific researches and clinical trials. When taking the analysis of longitudinal data, investigators are often confronted with missing data which will produce potential biases, even in...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Life care communities--Kentucky--Louisville; Congregate housing--Kentucky--Louisville; Older people--Housing--Kentucky--Louisville
As the older adult population in the United States continues its accelerated growth, there is a growing concern about the long-term care options for these elders. While nursing homes are no longer desirable and costly for federal and state...
Kwame Nkrumah framed a model of African unity and development, which stood out in
sharp contrast to the Western model of capitalist development and neo-liberal democracy.
Decades after his demise, the African Union which he co-founded with other...
Narration (Rhetoric)--Social aspects; Narration (Rhetoric)--Study and teaching
My dissertation examines instructor responses to a popular personal writing assignment, the literacy narrative. Previous studies have shown this assignment to be popular with instructors because of the reflection it is thought to generate; however,...
English language--Rhetoric--Study and teaching; English language--Composition and exercises--Study and teaching; Community colleges--Kentucky--Louisville
The introduction to this doctoral dissertation is an argument for locating Writing Across the Curriculum programs on the community-college campus for several reasons, among them the proximity of the disciplines on the community college campus, the...
O -linked β-N-acetylglucosamine ( O -GlcNAc) is an inducible, dynamically cycling, and reversible post-translational modification of serine/threonine amino acid residues of nucleocytoplasmic and mitochondrial proteins. O -GlcNAc transferase (OGT)...
Clustered longitudinal data is often collected as repeated measurements on subjects over time arising in the clusters. Examples include longitudinal community intervention studies, or family studies with repeated measures on each member. Meanwhile,...