Background: CHF is a chronic disease that affects nearly five million people each year; in which at least 500,000 are newly diagnosed cases. Patients diagnosed with this disease will be under a physician's care for the remainder of their life. It...
Aquatic ecosystems face major transformations as humans increasingly alter their environment by introducing exotic species and changing the temperature regime and nutrient availability of freshwater systems. The impacts of such alterations of...
Ground-level ozone forecast models were developed for the following middle and small metropolitan areas in Kentucky: Ashland, Bowling Green, Owensboro, and Paducah. These models were nonlinear regression models, based on models previously developed...
Cancer accounts for nearly one-quarter of deaths in the United States, exceeded only by heart diseases. Despite the development of various strategies to treat cancer, it remains one of the most deadly diseases worldwide due to the limited effects...
Intimate partner violence--Psychological aspects; Victims of family violence--Rehabilitation; Victims of violent crimes--Mental health; Creative writing--Therapeutic use; Post-traumatic stress disorder--Treatment
Described as important long-term consequences of trauma exposure, disruptions in emotional processes are regarded as central features of posttraumatic stress disorder (PTSD); however, the nature of these posttraumatic emotional disruptions remains...
Wound healing--Research; Wound healing--Animal models; Rabbits as laboratory animals
Ventral ear skin of the rabbit is a commonly used model for wound/ulcer studies; however the gradient effects of vascular ligation on epidermal stability has not been reported. In this study ischemic effects were studied after ligation of the...
Pancreatic islet transplantation is a very promising treatment for type I diabetes. Many clinical trials have failed due to early islet loss and immune rejection. Reactive oxygen species (ROS) have been demonstrated to be involved in graft damage...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
Blood flow--Measurement; Spinal cord--Wounds and injuries
Traumatic injury destroys blood vessels at the injury epicenter and is followed by local
angiogenesis and regional inflammation. Healing from injury depends on vascular health because
blood supply is directly responsible for the health and function...
McClellan, George Brinton, 1826-1885; Generals--United States--History--19th century; United States--History--Civil War, 1861-1865
This thesis is an examination of the factors that impacted the rise and fall of the military career of General George McClellan during the initial stages of the Civil War. It works almost exclusively with primary sources to gain a better...
The role of mothers, the constitution of families, and the power of their stories are the bedrock of my thesis, which is the first 90 pages of a novel entitled Playing House . In it, I hope to investigate the denotation and connotation of the words...
Background The anthracycline doxorubicin (DOX) is widely used as an effective antineoplastic drug. Cardiotoxicity leading to congestive heart failure is the primary factor limiting the clinical use of DOX. However, although a variety of approaches...
Kentucky--History--Civil War, 1861-1865; United States--History--Civil War, 1861-1865
In the early days of 1861, Kentucky, torn between her allegiance to the federal government and her sympathy for the South, with her citizenry so divided that hardly a family in the state stood united, vainly endeavored to carve out for herself a...
The purpose of this study was to compare the differences between 2 sets of ballistic stretching and 2 sets of a dynamic stretching routine on vertical jump performance. The intraclass reliability coefficients for maximum jump height, force, and...
Homeless persons--Services for--Kentucky--Louisville; Homelessness--Kentucky--Louisville; Inmates of institutions; Community-based social services--Kentucky--Louisville
The purpose of this study was to examine the link between various aspects of service utilization and the institutionalization of homeless individuals. The researcher wished to determine whether participation in various therapeutic, medical, and...
Healthy Hoops Kentucky; Asthma in children--Social aspects; Asthmatics--Social conditions
Asthma is the most common chronic disease among children aged 7 to 17 years of age in the United States. An average, one of every ten school-aged children has asthma, and 13 million school days are missed each year due to asthma. Interventions to...
Background: Emerging circulatory support devices that operate in counterpulsation to the native heart require synchronized timing of device ejection and filling on a beat-to-beat basis with the native heart using a patient's ECG. Surface leads are...
An increasing amount of healthcare resources is used for the treatment and prevention of contractures in patients with spinal cord injury (SCI), with stretch and passive movements remaining the most prominent intervention methods. The results of...
In this work, micro fabrication techniques are explored not only to simplify the production of complex lab on-a-chip devices (LOC), but also micro fabrication will be utilized to create intelligent design features that will enhance an...
