The inherited bone marrow failure syndromes (IBMFS) encompass a heterogeneous collection of rare disorders characterized by hematological abnormalities, generalized growth delays, and an increased incidence of malignant transformation. These...
Online organizations are always in search for innovative marketing strategies to better satisfy their current website users and lure new ones. Thus, recently, many organizations have started to retain all transactions taking place on their website,...
G-quadruplexes are thought to have biological importance, with studies based on small molecule interactions and quadruplex-interactive antibodies demonstrating their potential for formation in vivo. One potential biological function of quadruplex...
The secondary visual pathway, from the retina through the superior colliculus and pulvinar nucleus has been linked to spatial attention (Snow et aI., 2009; Arend et aI., 2008) movement planning and motor response to visual stimuli (Wilke et aI....
Healthy Hoops Kentucky; Asthma in children--Social aspects; Asthmatics--Social conditions
Asthma is the most common chronic disease among children aged 7 to 17 years of age in the United States. An average, one of every ten school-aged children has asthma, and 13 million school days are missed each year due to asthma. Interventions to...
Medical records--Data processing; Data mining; Medical care--Data processing; Coronary heart disease--Treatment
The goal of this study is to use a data mining framework to assess the three main treatments for acute myocardial infarction: thrombolytic therapy, percutaneous coronary intervention (percutaneous angioplasty), and coronary artery bypass surgery....
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
In 1979, the U.S. President's Commission on Foreign Language and International Studies stated that to function successfully in the next century, all adults would need more knowledge about our interdependent world, awareness of other peoples, and...
Achievement motivation in children; Personality and motivation; Motivation (Psychology); Poor children--Psychology
The current study was designed to better understand the early behavioral and emotional factors influencing young children's responses to challenge, which have important implications for learning. Understanding why children respond to challenge as...
Edgard Varese began composing "Deserts" in 1949 and completed it late in 1954. Scored for fifteen instruments, five percussionists and two tapes of organized sounds, "Deserts" comprises acoustic instrumental music and sections...
English language--Study and teaching--Foreign speakers--Case studies; English language--Study and teaching--Kentucky--Louisville
This thesis examined the structure and processes of several different organizations that offer English as a Second Language (ESL) classes in one Kentucky county. The purpose of the study was to analyze the structure of the organizations, and then...
From a computerized image analysis prospective, early diagnosis of lung cancer involves detection of doubtful nodules and classification into different pathologies. The detection stage involves a detection approach, usually by template matching,...
Stream riparian zones are ecotones between terrestrial and aquatic environments. Studying these areas in urban environments is important since they lie adjacent to stream water supplies. I conducted a study of riparian woody and groundcover...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
This thesis is a study of my current body of work, both formally and conceptually. It begins with an Introduction, explaining the origin of the term hybrid and the distinct advantages as well as disadvantages hybridization has on a species. It also...
Few previous studies have compared microbial communities in subterranean and surface environments. Chemical analyses used to characterize the surface and cave microbial environments indicated limited exchange between surface and subsurface waters....
Background: Helicobacter pylori (Hp) establishes life-long gastric infection in billions of humans, and is often responsible for diseases such as peptic ulcer and gastric cancer. Cumulative actions of genetic drift and natural selection over...
Nonparametric statistics; Estimation theory; Distribution (Probability theory)
Multistate models are a type of multi-variate survival data which provide a framework for describing a complex system where individuals transition through a series of distinct states. This research focuses on nonparametric inference for general...
Motivation (Psychology); Psychology and religion; Faith--Psychology
Religious motivation is a construct that has been the focus of decades of research. The "Religious Orientation Scale" (ROS) and variations of it, including the "Age Universal Intrinsic-Extrinsic Scale-12" (AUIES-12), are the...
College dropouts; Dropout behavior, Prediction of; Prediction of scholastic success
The persistence of second-year college students is gaining attention nationally. Vast resources have been dedicated to the retention of first-year students only to lose them at some point during the second year. Much of the research about the...
