Acrolein--Toxicology; Stem cells--Effect of pollution on
Acrolein is a common pollutant present in ambient air, automobile exhaust, and tobacco smoke. Previous studies show that exposure to acrolein increases cardiovascular disease risk. To determine whether acrolein affect cardiovascular regeneration,...
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Planar fiber-optic chips (FOC) take advantage of the evanescent field effects of side-polished fibers, exhibiting usefulness in fluorescence, absorbance, electrochemical investigations, and as presented here Raman spectroscopy. The fabrication of...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
The purpose of this dissertation was to demonstrate that a new method of direct intracellular energy delivery was effective in maintaining viability of in vitro Human Umbilical Vein Endothelial Cells (HUVECs) when exposed to chemical ischemia for...
Intimate partner violence--Psychological aspects; Victims of family violence--Rehabilitation; Victims of violent crimes--Mental health; Creative writing--Therapeutic use; Post-traumatic stress disorder--Treatment
Described as important long-term consequences of trauma exposure, disruptions in emotional processes are regarded as central features of posttraumatic stress disorder (PTSD); however, the nature of these posttraumatic emotional disruptions remains...
Integrated circuits--Design and construction; Integrated circuits industry--Technological innovations
Lithographic processes for printing device structures on integrated circuits plays a major role in the semiconductor industry. This project aims at designing and fabricating a programmable mask for a direct write lithography system which can...
Accelerated life testing; Reliability (Engineering); Service life (Engineering)
This dissertation is focused on finding lower confidence limits for the reliability of systems consisting of Wei bull components when the reliability demonstration testing (RDT) is conducted with zero failures. The usual methods for the parameter...
Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
Alcoholic liver disease (ALD) ranks among the major causes of morbidity and mortality in the world and effects millions of patients each year. Progression of ALD is well characterized and is actually a spectrum of liver diseases, which progresses...
The discovery of carbon nanotubes and subsequently graphene has led to an interest in carbon materials as sensing elements due to their unique properties. Graphene is a 2-dimensional material that has a large surface area that can be exposed to...
Oxygen is critical to aerobic metabolism, but hyperoxia is cytostatic and cytocidal. The precise mechanisms involved in hyperoxic cell injury remain incompletely understood although there is substantial support for the possibility that hyperoxia...
Cerium dioxide or ceria, CeO2, has been widely used in industry as catalyst for automotive exhaust controls, chemical mechanical polishing (CMP) slurries, and high temperature fuel cells because of its unique metal oxide properties. This well-known...
Universities and colleges--Mergers; Education, Humanistic--United States--Case studies; Community colleges--Curricula; Educational change--United States--Case studies
This dissertation is an examination of the state of the liberal arts curriculum in community colleges in three geographic regions of the United States. From a constructivist paradigm and using globalization theory as a theoretical framework, this...
Star Wars films--History and criticism; Myth in motion pictures; Lucas, George, 1944-
The Star Wars franchise is one of the most successful film series of all time. The original three
movies, along with the more recent three prequels, serve as the foundation to a vast empire of
Star Wars television shows, action figures, comic...
Elastomer degradation when exposed to chloraminated potable water is dependent on a number of poorly understood factors. Temperature and chloramine concentration are both believed to play roles, however, they have not been adequately defined. In...
Dentists--Attitudes; Endodontics--Study and teaching; Medical referral
The decision by a general dentist to treat or refer a patient needing endodontic therapy may be based on multiple variables. Students attending dental schools with endodontic specialty programs could be exposed to a referral system with endodontic...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
Wounds and injuries--Treatment; Drug delivery systems
Wounds care and management is one of the most basic needs in the medical setting. Burn wounds, trauma wounds, pressure ulcers and bedsores are just some of the many types of wounds that need to be treated quickly and efficiently. Take for instance...
