Nosocomial infections; Catheterization--Complications; Drug resistance in microorganisms
Catheters represent an essential part of the management of critically and chronically ill patients. However, their use is often plagued by catheter related blood stream infections (CRBSIs), which are associated with increased morbidity, hospital...
Research over the past twenty five years has led to the development of the hypothesis that colorectal cancer is caused by the accumulation of mutations in tumor suppressor genes and proto-oncogenes. The last ten years has also revealed that the...
Self-control in children; Crime and race; Parent and teenager; Teenagers--Family relationships
This study seeks to examine whether racial disparities in offending can be explained through self-control theory. The study utilized longitudinal responses of a nationally representative sample of 1700 adolescents. Parenting and self-control...
This dissertation examines the competing views of multilingualism that shape U.S. and Canadian post-secondary literacy education. Drawing on education, English studies, globalization theory, applied linguistics, translation studies,...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
Recent studies indicate post-translational deacetylation by members of the superfamily of histone deacetylase complexes (HDACs) is necessary for oligodendrocyte precursor cell (OPC) differentiation into mature oligodendrocytes (OLs). However, it...
More than 50% of the total energy produced is typically rejected in the form of waste heat from various processes. The grand challenge is that most of this waste heat is released at temperatures much lower than 1000 C, which makes it difficult to...
The current study examined how Disclosure, Stereotype Disconfirming Information, and Stereotype Disconfirming Information and Disclosure Combined) influences an individual's stigma (stereotype endorsement, emotional reactions, and discrimination)...
Trucking--Management; Freight and freightage--Cost control; Freight and freightage--Planning
Freight imbalance is a problem that negatively affects drivers and carriers within the truckload trucking industry. One result of this problem is that the industry experiences high annual driver turnover, exceeding 130% annually. The turnover can...
An individual's role set consists of a variety of different roles (Biddle, 1979; Madsen & Hammond, 2005). Parent, spouse, student, and even sports fan, all constitute roles within one's role set. Fulfilling role demands requires time, energy,...
Nerves--Regeneration; Spinal cord--Wounds and injuries--Treatment
These studies set out to identify strategies to rescue and repair the adult nervous system. First, we investigated the role of ciliary neurotrophic factor (CNTF) in 5HT1A receptor-induced neurogenesis in the rodent brain. Systemic treatment with an...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Drug delivery systems; Curcumin--Therapeutic use--Administration
Curcumin, a plant derived compound has shown significant potency against various chronic diseases like cancer in cell culture and animal studies. However, the introduction of this compound into clinical setting is limited by its poor oral...
Rising environmental concerns due to our rising population ad energy demand along with our excessive dependence on fossil fuels has created an urgent need to find clean, renewable and carbon free source of energy. Photoelectrochemical (PEC) water...
Sleep disorders in children; Children--Sleep; Blind children
Research has confirmed that individuals with blindness have an increased risk of
developing sleep problems; this is especially problematic for families with young
children who are blind. Not only does the lack of sleep impact the growth...
The objective of my dissertation research was to determine the role of chemical signals in conveying information regarding an individual's health status and suitability as a mate in humans and to examine the role that commensal microflora play in...
College students--Attitudes; College dropouts; Dropout behavior, Prediction of; Academic achievement; Prediction of scholastic success
This study explored the relationship between engagement in educationally purposeful activities during the first year of college and academic achievement, persistence, and graduation. The study focused on the impacts of engagement on student...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
New firms face financial constraints that could hinder firm performance. Yet founders exhibit persistence and resourcefulness in building their new ventures and finding solutions to their financial constraints. The use of financial theories that...
This dissertation represented an examination of the interrelationships between psychological gender (i.e., masculinity, femininity, androgyny, and undifferentiated), biological gender (i.e., male and female), gender role conflict, self-esteem, and...
