Congenital stationary night blindness 1 (CSNBl) is a genetic disorder characterized in humans by night blindness, low visual acuity and myopia. CSNB 1 is caused by defects in genes that are involved in signaling between photoreceptors and...
Israel--Social conditions; Israel--Social life and customs
Times Square went mad with noise and excitement,
and a small freighter slipped from its Brooklyn berth into
the drama of the night. It was December 31, 1949--midnight-January
1, 1950; and I was on my way to the world in general
and Israel and the...
Chlamydia trachomatis is an obligate intracellular pathogen that utilizes a type III secretion system to enter mammalian cells and establish an intracellular niche. TARP, the translocated actin recruitment protein, is a chlamydial invasion protein...
The immune system is of profound importance for host survival due to its ability to clear many acquired diseases. In case of infections and cancer, disease arises due to under-performance of immune system. Whereas in autoimmunity and...
Here, I address the function of the carboxy-terminal hydrophobic helix of the pro-apoptotic protein Bax. There has been considerable controversy as to whether this sequence is required for the targeting and insertion of Bax into the mitochondrial...
Gene therapy; Spinal cord--Wounds and injuries; Tissue engineering
The combination of viral mediated gene delivery, tissue engineering, and Schwann cell (SC) transplantation offer a promising strategy to enhance axonal regeneration and functional recovery following spinal cord injury (SCI). The rationale and...
Sick--Personal narratives; Sick--Psychology; Sick--Biography--History and criticism; Narrative medicine
This dissertation uses a phenomenological and sociological lens to explore how non-fiction illness narratives help us understand how perception of the self is disrupted because of serious illness or injury. Specifically, I use the French...
Women agricultural laborers--England--History--19th century; Women agricultural laborers--United States--History--19th century; Women in agriculture--England--History--19th century; Women in agriculture--United States--History--19th century; Women...
This thesis is a historical study comparing the work-lives African-American and English nineteenth-century, field-working women. It focuses on the ideology and structure of the gender division of labour as it formed and informed the lives of these...
The area of Knowledge discovery and data mining is growing rapidly. Feature Discretization is a crucial issue in Knowledge Discovery in Databases (KDD), or Data Mining because most data sets used in real world applications have features with...
Art museums--Collection management; Rowling, Charles, 1935-2008; Kentucky Museum of Art and Craft
This Curatorial project examines issues that museums face in the documentation of permanent collections, using the Kentucky Museum of Art and Craft (KMAC) and its piece Angel, by Charles Rolwing, as specific examples. The project focuses on museum...
Psychic trauma in art; Psychoanalysis and art; Art--Psychological aspects; Salomon, Charlotte, 1917-1943. Leben oder theater?
This thesis explores the presence of the dialectic of trauma in Charlotte Salomon’s magnum opus, Life? or Theatre?, a series of more than seven hundred paintings created during her time in exile in France between 1941 and 1942. In this series,...
Recent studies indicate post-translational deacetylation by members of the superfamily of histone deacetylase complexes (HDACs) is necessary for oligodendrocyte precursor cell (OPC) differentiation into mature oligodendrocytes (OLs). However, it...
Sartre, Jean-Paul, 1905-1980--Criticism and interpretation; Percy, Walker, 1916-1990--Criticism and interpretation; Hopper, Edward, 1882-1967--Criticism and interpretation; Nichols, Mike--Criticism and interpretation; Existentialism in art;...
Jean-Paul Sartre's existential philosophy concerns the free human individual,
particularly his possibilities to continuously create his own identities. Human existence is
never defined by objects, and he is only determined by his own actions. As...
To manage large image databases, Content-Based Image Retrieval (CBIR) emerged as a new research subject. CBIR involves the development of automated methods to use visual features in searching and retrieving. Unfortunately, the performance of most...
Scheduling--Computer programs; Social work administration--Data processing; Public welfare administration--Data processing
The client flow of the Kentucky Cabinet for Health and Family Services is a complex process that deals with a high volume of clients on any given beginning half of the month. A simulation model of an average busy day in the system was built using...
In fulfillment of the thesis project requirement for the Master of Fine Arts Degree at the University of Louisville, I portrayed the multiple roles of Clytemnestra, Electra and Athena in Dr. Steve Schultz's translation of Aeschylus'...
Nanomaterials have many intriguing applications in biology and medicine. Unique properties such as enhanced electrical properties, increased chemical reactivity and resistance to degradation, novel optical properties and comparable size to that of...
Gary Snyder's poetry conveys Zen states of consciousness through unconventional grammar and syntax. From his first book Riprap in 1959 to his last collection of poems, Mountains and Rivers Without End in 1996, he has confronted the challenge of...
The role of mothers, the constitution of families, and the power of their stories are the bedrock of my thesis, which is the first 90 pages of a novel entitled Playing House . In it, I hope to investigate the denotation and connotation of the words...
Pattern perception--Data processing; Pattern recognition systems; Land mines--Detection; Data mining
For complex detection and classification problems, involving data with large intra-class variations and noisy inputs, no single source of information can provide a satisfactory solution. As a result, combination of multiple classifiers is playing...