Neurosphere forming cells (NSFCs) have been derived from cultures of adult olfactory neuroepithelium obtained from patients and cadavers in serum rich medium. These neural progenitors remain undifferentiated when maintained in serum rich medium but...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
Eating disorders in children; Behavior modification
Feeding disorders occur when a child rejects significant amounts of food or drink. Food refusals are maintained by factors which may be behavioral based, due to structural impairments, or a combination of the two. One of the first steps to...
The purpose of this dissertation was to demonstrate that a new method of direct intracellular energy delivery was effective in maintaining viability of in vitro Human Umbilical Vein Endothelial Cells (HUVECs) when exposed to chemical ischemia for...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
One of the most nationally-recognized, two-year legislative reform initiatives in the U.S. began in Kentucky with the passage of the Kentucky Postsecondary Education Improvement Act of 1997 (HB1). This exploratory, cross-sectional, correlational...
Pancreatic islet transplantation is a very promising treatment for type I diabetes. Many clinical trials have failed due to early islet loss and immune rejection. Reactive oxygen species (ROS) have been demonstrated to be involved in graft damage...
Enzymatic hydrolysis is an important, but time limiting step in the process of converting biomass into ethanol. High solids concentrations are desired in order to minimize reactor size and achieve a higher concentration of glucose in the end...
The airline regulatory communities are interested in methods that can access degradation in the polymer insulation of aging aircraft wiring. This study investigates the response of bulk polymer films and aircraft wiring under indentation; changes...
The pulvinar is the largest nucleus of the human dorsal thalamus and is affected in a variety of brain disorders, such as schizophrenia. The experiments described in this dissertation elucidate key features of tecto-pulvino-cortical pathways as a...
Griffithsin (GRFT) is a carbohydrate binding protein derived from the red alga Griffithisia sp. that has been shown to effectively interfere with the cellular attachment and infectivity of a number of viruses, including HIV-1. However, it is...
Long-term care facilities--Patients; Older people--Dental care
Oral health is a critical component of every individual's general health and well-being. There is evidence that consistently demonstrates that age, poverty, education levels, minority status, and living in a rural area are risk factors for poorer...
Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
Middle school teachers--Kentucky; Middle school students--Kentucky; Academic achievement; Teachers--Job satisfaction--Kentucky; School environment--Kentucky
This quantitative study focused on 760 Kentucky middle school teachers in 28 school districts across the state of Kentucky. The Pearson r was used to determine the relationship between the following variables identified in the study: (a) school...
This paper explores issues of identity and difference in art and its institutions through a historiographic study of two landmark exhibitions, "The Other Story: Afro-Asian Artists in Post-War Britain" (1989) and the 1993 Whitney Biennial....
Mixing machinery; Production engineering--Case studies
A processing facility in Trenton, Ky owned by HydroSolutions is in need of modernization in order to increase efficiency in the mixing process, improve the safety of the facility, and give the facility the ability to expand in the future. The main...
In the year 1573 when Shakespeare and Marlowe were already boys of nine, Chapman in adolescence, Spenser, Lyly and Richard Hooker men of twenty, John Donne, then important to only a few but destined to the company of royalty, was born. Walton...
Alcohol; Distillation; Alcoholic beverages; Corn--Utilization; Whiskey industry
In the whisky industry there is a balance between the desire to adhere to the traditional production process and the desire to increase profit margins. One solution that follows both stipulations is to increase the alcohol yield of a given batch of...
A common problem faced by most organizations in today's world is one of worker-task assignments. Assigning a large number of complex tasks to workers at various training levels can be a complicated process which has the potential to cost or to save...
All terrain vehicles--Automatic control; Motor vehicles--Automatic control; Intelligent control systems
When tracked vehicles traverse terrain such as sand, soil, or even concrete,
they may encounter a variance in density or viscosity of the medium that the
vehicle is traveling along. When this happens, one track begins to move faster or
slower...
