Chapter 1 detailed the synthesis method of hydroxamate peptides derivatives of pentapeptide Ac-PHSXX\'-N-NH2 by solid phase hydroxamate peptide synthesis method. The glutamic acid/aspartic acid side chain was modified to hydroxamic acid by on resin...
This dissertation describes (1) size-dependent electrochemical oxidation/stripping of gold and silver nanoparticles (NPs), (2) alloying of copper with gold nanoparticles at underpotential deposition potentials, (3) electrochemical characterization...
This dissertation describes galvanic exchange of silver (Ag) nanostructures with PdCl42- in 1) various PdCl42- concentrations, 2) the presence of 0.1 M cetyitrimethylammonium bromide (CTAB), and 3) the presence of 0.1 M potassium bromide (KBr). It...
This dissertation describes new procedures for synthesizing and purifying Au and Au/Ag nanoplates directly on surfaces as well as controlled binding of proteins to their surface. It also describes fundamental changes in the optical properties of Au...
The research in this dissertation describes a simple electrochemical approach for fabricating nanoscale (metal/metal) or molecular (metal/polymer or self assembled monolayer (SAM)/metal) junctions. The fabrication involves metal deposition on one...
This dissertation deals with various imidazole compounds with emphasis on hydrogen bond interactions and weaker intermolecular forces. New amide functionalized polyimidazole metal binding pockets are able to form intramolecular six-membered...
Energy independence requires that the nation reduce its dependence on foreign oil imports. This can be achieved through electrification of transportation vehicles if proper battery technology can be developed. In addition, the renewable energy...
Most of the structures in submillimeter-scale engineering are created from thin films, making them essentially two-dimensional (2D). Significant work has been done to fabricate 3D structures using self-folding, a deterministic form of...
Nitrile hydratase (NHase) is a metalloenzyme that contains a non-heme iron (III)
or non-corin cobalt (III) in a non-redox active role. NHase is used as biocatalyst in the
industry for the hydrolysis of nitriles to arnides. The trivalent metal ions...
The oxidation of metallothiolates is complicated by "non-innocence" or potential
redox activity of sulfur to yield thiyl (RS•) radicals. In some instances, the one-electron
oxidation of metal thiolates yields a product with the unpaired...
Our research activities are based on the catalytic systems that provide resource-saving synthetic methodologies through gold-catalyzed reactions of alkynes and alkenes. We have worked on three applications: i) an effective and straightforward...
This thesis describes 1) the kinetics of vapor phase place exchange reactions on films of gold monolayer protected clusters (Au MPCs) to alter the functionality of the Au MPCs, 2) applications of the reaction for altering chemiresistive sensing...
This study expands our efforts to make a new class of Pt (II) compounds analogous to cisplatin and its derivatives using sterically hindered ligands. Pt compounds in this series have been synthesized using specially designed pyridine and...
The separation of C02 from light gases is a very important environmental and energy issue. The state-of-the-art process for the purification of C02 uses amine adsorption, which is a complex, and costly. Membrane technology is far less expensive...
Liquid gallium (Ga) spontaneously alloys with thin films of metals such as Ag, Au, Pt Al, and Cu at near or even below room temperature resulting in rapid self-assembly of nanostructures. In this dissertation, studies of the formation of these...
This research was performed to establish the feasibility of using Direct Metal Deposition (DMD) technology to deposit nickel powder to a nickel substrate. The substrate is electrodeposited pure nickel, and the material to be deposited is Metco...
Microhotplates for metal oxide gas sensors are fabricated using platinum microheaters and tested. Power consumption is monitored and temperature distributions are observed using infrared microscopy. Temperature line traces are extracted from the...
The motivation to determine a viable alternative to petroleum based energy has risen in recent years due to increased greenhouse gas emissions, environmental pollution, and the fear of exhausting oil and natural gas reserves. Biodiesel derived from...
The purpose of this research is to understand how the process parameters surrounding the Direct Metal Deposition (DMD) process affect the properties of the deposition. The powder used in this research is pre-alloyed titanium powder (Ti-6Al-4V),...
