Emergency management--Kentucky; Assistance in emergencies--Kentucky; Disaster relief--Kentucky; Transportation--Planning
Large-scale emergencies caused by earthquake, tornado, pandemic flu, terrorism attacks and so on can wreak havoc to communities. In order to mitigate the impact of the events, emergency stockpiles of food, water, medicine and other materials have...
Radio frequency allocation; Wireless communication systems
Recently, the need for wireless and mobile communications has grown tremendously and it is expected that the number of users to be supported will increase with high rates in the next few years. Not only the number of users, but also the required...
Implementing Job Rotation as a manufacturing method is beneficial to production efficiency, reduction of labor cost, operator satisfaction, and Work-related Musculoskeletal Disorders (WMSDs) reduction. In this thesis, the steps of simulating the...
Digital control systems; Computer security; Process control--Computer programs; Supervisory control systems--Security measures
Supervisory control and data acquisition (SCADA) systems are networked control systems used in many critical infrastructure areas such as power water and transportation. Many of these systems continue to use legacy field devices that lack cyber...
Age-related macular degeneration (ARMD) and retinitis pigmentosa (RP) are the two leading causes of blindness in the world today. Despite enormous efforts and advances in clinical treatment of eye diseases, there is no established method or cure of...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Vascular injury and chronic arterial diseases such as atherosclerosis and restenosis result in exposure of vascular smooth muscle cells (VSMCs) to increased concentrations of growth factors triggering a change from a contractile to a synthetic...
Night vision--Genetic aspects; Vision disorders--Genetic aspects
Mutations in the NYX gene, encoding the novel protein nyctalopin, cause human congenital stationary night blindness type 1 (CSNB1). CSNB1 is an X-linked recessive condition and is identified by a loss of the electroretinogram (ERG) b-wave while the...
In this work, micro fabrication techniques are explored not only to simplify the production of complex lab on-a-chip devices (LOC), but also micro fabrication will be utilized to create intelligent design features that will enhance an...
This quantitative dissertation examines outcomes of a required service-learning program at a faith-based institution. Two hundred and ten students completed a pre/post survey administered to a sophomore level class about background, educational...
Colon (Anatomy)--Cancer--Genetic aspects; Cancer cells--Mathematical models
Research over the past twenty five years has led to the development of the hypothesis that colorectal cancer is caused by the accumulation of mutations in tumor suppressor genes and proto-oncogenes. The last ten years has also revealed that the...
Industrial efficiency; Industrial management; New products--Economic aspects
In today's market customers are increasingly demanding a greater number of options in the products they purchase. Offering products in greater variety helps industries cater to a wider range of customers. However, at the same time, this product...
Grading and marking (Students)--Data processing; Discourse analysis--Data processing; Instructional systems--Design
In recent years the use of Tablet PCs in education has received a great deal of attention. Improved note-taking and lecture presentation have been the main focus of Tablet PCs in education. Currently, grading of student work collected as digital...
Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased...
Human adenoviruses (Ads) can infect and replicate in cells at different cell-cycle stages. Ads with the E1 B55K deletion preferentially replicate in cancer cells and cause oncolysis. Our laboratory has previously shown that the Ad E1 b gene is...
Rising environmental concerns due to our rising population ad energy demand along with our excessive dependence on fossil fuels has created an urgent need to find clean, renewable and carbon free source of energy. Photoelectrochemical (PEC) water...
Writing centers; English language--Rhetoric--Study and teaching (Higher); Tutors and tutoring
Using Gloria Anzuldula's text Borderlands/La Frontera: The New Mestiza and Bruce Homer and Min-Zhan Lu's 2000 article, "Expectations, Interpretations and Contributions of Basic Writing" as conceptual framework, I conducted my dissertation...
Here, I address the function of the carboxy-terminal hydrophobic helix of the pro-apoptotic protein Bax. There has been considerable controversy as to whether this sequence is required for the targeting and insertion of Bax into the mitochondrial...
This study focuses on the variation in structural response to synthetic ground motions derived from the latest attenuation models developed for the Central Eastern United States (CEUS) and used by the USGS to develop the latest edition (2008) of...
Heuristic; Production management; Personnel management--Data processing
The Naval Surface Warfare Center wishes to create a task assignment schedule
with a minimal training cost for workers to raise their skills to the required levels. As the
number of workers, skills, and tasks increase, the problem quickly becomes...
