This project uses the work of Michel Foucault and Lynne Huffer to examine the creation of the transsexual subject in 1950s American sexology through the Cartesian subject. I argue that medical professionals utilized the Cartesian subject as a...
Women air pilots; Women--Recreation--Social aspects; Leisure--Social aspects
Serious leisure theory (Stebbins, 1992) is used to frame this examination of women's long-term involvement in airplane piloting. Through in-depth, semi-structured telephone and e-mail interviews with women having over 15 years experience as private...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
The topic of this dissertation is the automation of the process of extracting understandable patterns and rules from data. An unprecedented amount of data is available to anyone with a computer connected to the Internet. The disciplines of Data...
Enzymatic hydrolysis is the most common method of producing fermentable sugars from lignocellulosic biomass. Limitations to this step include the high cost of enzymes, and the time required to process the biomass. To increase the throughput and...
Ribosomal biogenesis failure may contribute to neurodegenerative diseases, while its excessive activation has been shown to drive tumor growth. As ribosomal production is initiated and regulated by the Pol1-mediated transcription of rRNA genes in...
The rate of overqualification, defined as a person having more education or skills than
their job requires them to have, has continued to grow since the issue was first identified
as a significant problem. Though evidence that suggests the rate of...
The separation of C02 from light gases is a very important environmental and energy issue. The state-of-the-art process for the purification of C02 uses amine adsorption, which is a complex, and costly. Membrane technology is far less expensive...
Down syndrome--Patients; Williams syndrome--Patients; Social interaction in children; Social perception in children
The present project examined the regulatory function of social referencing in two neurodevelopmental disorders that have been well defined genetically and are characterized by differing patterns of socio-cognitive development: Down syndrome (DS)...
Energy independence requires that the nation reduce its dependence on foreign oil imports. This can be achieved through electrification of transportation vehicles if proper battery technology can be developed. In addition, the renewable energy...
Embryonic development requires the orchestration of temporally precise genetic events that culminate in the formation of a complete organism. The molecular mechanisms responsible for ontogenesis are regulated by environmental and somatic factors in...
Quorum sensing (Microbiology); Cellular signal transduction; Bacterial genetics
Quorum sensing in the oral pathogen Aggregatibacter actinomycetemcomitans is dependent upon the soluble signaling molecule AI-2, but it is not known how the initial detection of AI-2 is coupled to the downstream regulation of gene expression that...
Cardiology--Research--Methodology; Microfluidics--Equipment and supplies
Cardiovascular disease (CVD) is the leading cause of death in the United States and accounts for nearly 1,372,000 deaths each year. In addition, ~81 million Americans suffer from some form of CVD. Understanding the molecular basis of various...
Male college students--Social conditions; College freshmen--Social conditions; People with social disabilities--Education (Higher)
This dissertation is a case study involving four, first generation, working class,
college students. The dissertation study chronicled the experiences of these students
during their first semester at the college. In order to more effectively focus...
The facility layout problem is a combinatorial optimization problem that involves determining the location and shape of various departments within a facility based on inter-department volume and distance measures. An optimal solution to the problem...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Rising concerns about dependency on fossil fuels in the 21st century has sparked a growth in research for renewable energy sources. One renewable energy production process of interest is the reduction of cellulose into fermentable sugars by means...
Type 2 diabetes presents a public health crisis and a global pandemic. Successful management of diabetes requires engagement in a daily regimen of self-care behaviors to achieve optimal glycemic control and to reduce the severity of...
This research project describes the application of a master/slave configuration of processors to study a comparison of alternative material handling configurations for automated manufacturing. Such a study usually requires a large number of...
Many dedicated-use computer systems sold as complete products require a turn-key design delivered to the customer. This requires a system which is stable, secure, and serviceable. Adaptability of the system to existing software applications is a...
