Residential buildings account for a large portion of total energy consumption in the United States. Residential energy usage can be dramatically reduced by improving the efficiency of building envelope systems. One such method is to incorporate...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
The broad long-term objectives of this research project are to increase the percentage of women who seek care for urinary incontinence. The specific aims of this research project are: (1) Use Lauver's Theory of Care Seeking Behavior to identify...
Previous research has indicated the important role of visual information in the speech perception process. These studies have elucidated the areas of the brain involved in the processing of audiovisual stimuli. The McGurk effect, an audiovisual...
Among gynecological malignancies, carcinoma of the cervix is the leading cancer type worldwide. Conversely, vaginal tumors account for an incidence of approximately 1-2% of lower genital tract malignancies. Interestingly, the major shared risk...
Energy independence requires that the nation reduce its dependence on foreign oil imports. This can be achieved through electrification of transportation vehicles if proper battery technology can be developed. In addition, the renewable energy...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
More than 50% of the total energy produced is typically rejected in the form of waste heat from various processes. The grand challenge is that most of this waste heat is released at temperatures much lower than 1000 C, which makes it difficult to...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
This dissertation is an exploratory study of the indicators of receptivity that communities portray towards international service-learning programs. Historically, programs such as service learning programs choose communities and other working...
This work presents a novel comprehensive effort to understand the fluid dynamics within orbiting dishes and the effects of the resulting oscillating fluid flow on shear and endothelial cellular responses within the dishes. It is well documented...
A common research interest in medical, biological, and engineering research is determining whether certain independent variables are correlated with the survival or failure times. Standard statistical techniques cannot usually be applied for...
This dissertation describes galvanic exchange of silver (Ag) nanostructures with PdCl42- in 1) various PdCl42- concentrations, 2) the presence of 0.1 M cetyitrimethylammonium bromide (CTAB), and 3) the presence of 0.1 M potassium bromide (KBr). It...
While housing tenure choice by the general population and minorities has been studied by a good number of researchers, current research on the tenure choice by immigrants has been limited and sporadic. This study provides further understanding of...
Protein C (PC) is an important anticoagulant, antithrombotic, and antiinflammatory in blood plasma. PC deficiency can lead to severe venous thrombotic events, including lung embolism, stroke, and heart attack. In the body, PC is activated only when...
Previous experimental studies on static, bio-inspired corrugated wings have shown that they produce favorable aerodynamic properties such as delayed stall compared to streamlined wings and flat plates at high Reynolds numbers (Re ≥ 4x104). The...
Cerium dioxide or ceria, CeO2, has been widely used in industry as catalyst for automotive exhaust controls, chemical mechanical polishing (CMP) slurries, and high temperature fuel cells because of its unique metal oxide properties. This well-known...
Heart--Hypertrophy; Hydrogen sulfide--Therapeutic use
Background: Although matrix metalloproteinase (MMPs) and tissue inhibitor of metalloproteinase (TIMPs) play a vital role in tumor angiogenesis and TIMP-3 causes apoptosis, their role in cardiac angiogenesis is unknown. Interestingly, a disruption...
School-based management--Kentucky; School management and organization--Kentucky
This study examined the perceptions of Kentucky SBDM council members concerning the productivity and efficacy of the councils. The major variables studied were council member position, council member demographic characteristics, perceived efficacy,...
