Urinary incontinence is a major public health problem affecting 30% of community dwelling women aged 35-85. Urinary incontinence may have a significant impact on activities of daily living depending on the severity of symptoms. Women with urinary...
The broad long-term objectives of this research project are to increase the percentage of women who seek care for urinary incontinence. The specific aims of this research project are: (1) Use Lauver's Theory of Care Seeking Behavior to identify...
Embryonic development requires the orchestration of temporally precise genetic events that culminate in the formation of a complete organism. The molecular mechanisms responsible for ontogenesis are regulated by environmental and somatic factors in...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Human arylamine N-acetyltransferase (NAT) is a phase II cytosolic enzyme that occurs as two isozymes, NAT1 and NAT2. This family of polymorphic enzymes catalyzes the detoxification and/or activation of many aromatic and heterocyclic amine drugs and...
