The trucking industry is the largest freight sector, making up about 70 percent of all domestic shipment in the United States and contributes greatly the American economy. About 10 billion tons of goods are shipped annually and of that, about...
In the present study, we report the synthesis of thermally stable mesoporous gallium oxide and novel gallium-niobium mixed oxides employing Evaporation Induced Self-Assembly (EISA), Self-Assembly Hydrothermal-Assisted (SAHA) and Self-Assembly...
This dissertation describes research focused on the synthesis, polymerization and
applications of cationic aminooxy lipids. An efficient and convenient method was
developed to stabilize liposomes using 'click chemistry'. The 'click...
Premenopausal women have fewer and less severe strokes when compared to postmenopausal females and aged matched males. The most obvious factor that could account for the observed difference is the physiological activity of Estrogen. Numerous...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
O -linked β-N-acetylglucosamine ( O -GlcNAc) is an inducible, dynamically cycling, and reversible post-translational modification of serine/threonine amino acid residues of nucleocytoplasmic and mitochondrial proteins. O -GlcNAc transferase (OGT)...
Drug delivery systems; Curcumin--Therapeutic use--Administration
Curcumin, a plant derived compound has shown significant potency against various chronic diseases like cancer in cell culture and animal studies. However, the introduction of this compound into clinical setting is limited by its poor oral...
Griffithsin (GRFT) is a carbohydrate binding protein derived from the red alga Griffithisia sp. that has been shown to effectively interfere with the cellular attachment and infectivity of a number of viruses, including HIV-1. However, it is...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Hypoxia is characterized by an inadequate oxygen supply to the tissues in
proportion to their metabolic needs, and is a primary factor in traumatic CNS
injury, strokes, cardiopulmonary diseases, and obstructive sleep apnea. The
cAMP-dependent...
Brief Overview of the Problem: The Environmental Protection Agency (EPA), a government funded agency, provides both legislative and judicial powers for emissions monitoring in the United States. The agency crafts laws based on self-made regulations...
It has been shown that GSK3 β plays a critical role in the inflammation response by differentially regulating MyD88-dependent pro- and anti-inflammatory cytokines production in TLR4-stimulated innate immune cells. The work included in this...
Colorectal cancer is the fourth most common cancer, and the fourth leading cause of cancer related death in the United States. It also happens to be one of the most preventable cancers provided an individual performs a regular screening. For years...
Social anxiety is prevalent and debilitating. Contemporary models of social
anxiety posit that negative, self-focused thought aids in the maintenance of social anxiety
symptoms. Although these models emphasize in-situation cognition, recent...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
Self-efficacy; Psychological abuse; Identity (Psychology); Women college students--Mental health
The current research proposed that psychological abuse within an intimate relationship erodes one's self-efficacy and aimed to demonstrate a negative relationship between past psychological abuse and how one reacts to a challenge. It was...
In the electronic and microfabrication industry, die separation is one of the most critical steps in producing an undamaged, stand-alone micro-scale device. For silicon based devices, it is the predominant step governing resistance to die failure...
Nanoparticles; Imaging systems in medicine; Imaging systems in biology
Gold nanoparticles (GNPs) have shown beneficial properties for biomedical use, e.g., their non-toxic nature and surface properties for easy modification. Upon receiving light, they generate a strong surface plasmon field, which can alter the...
This research project describes the application of a master/slave configuration of processors to study a comparison of alternative material handling configurations for automated manufacturing. Such a study usually requires a large number of...
The impact of socioeconomic status on the diagnosis, treatment, survival, and overall quality of life in persons with cancer has been well documented. Yet, many studies overlook the relevance of socioeconomic factors when measuring the impact of...