Standard regularity assumptions for regression models are not satisfied in segmented regression models with an unknown change point, and consequently standard asymptotic results and inferential methods for confidence estimation are not applicable....
This study expands our efforts to make a new class of Pt (II) compounds analogous to cisplatin and its derivatives using sterically hindered ligands. Pt compounds in this series have been synthesized using specially designed pyridine and...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Osteoporosis in women--Prevention; Osteoporosis--Treatment; Hip joint--Fractures--Prevention
Low-trauma fractures of older women are a major public health burden. Fractures of the hip and spine are some of the primary causes of chronic pain, functional impairment, and disability among the elderly [1]. The underlying cause of these...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
Clustered longitudinal data is often collected as repeated measurements on subjects over time arising in the clusters. Examples include longitudinal community intervention studies, or family studies with repeated measures on each member. Meanwhile,...
The area of total coloring is a more recent and less studied area than vertex and edge coloring, but recently, some attention has been given to the Total Coloring Conjecture, which states that each graph's total chromatic number xT is no greater...
The classification of self-dual codes has been an extremely active area in
coding theory since 1972 [33]. A particularly interesting class of self-dual codes
is those of Type II which have high minimum distance (called extremal or...
The Combinatorial Nullstellensatz can be used to solve certain problems in combinatorics. However, one of the major complications in using the Combinatorial Nullstellensatz is ensuring that there exists a nonzero monomial. This dissertation looks...
The purpose of this study was to determine if training has a protective effect on endothelial function following the consumption of a high-fat meal. Twenty young males classified as trained or untrained underwent vascular and blood lipid testing...
A k-term quasi-progression of diameter d is a sequence {Xl,... ,xk} for which there exists a positive integer l such that l < Xi-Xi-1 < l+d, for all i = 2, ... ,k. Quasi-progressions may be thought of as arithmetic progressions with a certain...
Many businesses have poor IT infrastructure and are in need of a major overhaul. University of Louisville Properties (ULP), in particular, needed the ability to share files between staff, backup data, secure data, and eliminate viruses and malware....
Regression analysis is a statistical method used to relate a variable of interest, typically y (the dependent variable), to a set of independent variables, usually, X1, X2,...,Xn . The goal is to build a model that assists statisticians in...
Academic achievement--Psychological aspects; College students--Psychology
Researchers have studied the concepts of optimism and pessimism as traits, expectations, strategies, and styles of explaining outcomes. Explanatory style and the strategy of defensive pessimism are two of these areas. In general, optimistic...
Ten algal isolates were obtained from soil into axenic culture and placed into defined media containing from 0 to 50 ppm of DDT, 2, 4-D,2,4,5-T, rotenone, or malathion (in two purities, 95 and 99%). For nine of the isolates, growth was measured...
Radio frequency allocation--Mathematics; Wireless communication systems--Mathematical models; Frequency spectra--Mathematical models
Multidimensional frequency estimation is a classic signal processing problem that has versatile applications in sensor array processing and wireless communications. Eigenvalue-based two-dimensional (2-D) and N -dimensional ( N -D) frequency...
We formulate an integro-difference model to predict the growth and spatial
spread of a perennial plant population with an age-structured seed bank. We allow
the seeds in the bank to be of any age, producing an infinite system of equations.
The...
Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
Outerplanar graphs are planar graphs that have a plane embedding in which each vertex lies on the boundary of the exterior region. An outerplanar graph is maximal outerplanar if the graph obtained by adding an edge is not outerplanar. Maximal...
A common research interest in medical, biological, and engineering research is determining whether certain independent variables are correlated with the survival or failure times. Standard statistical techniques cannot usually be applied for...