Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Introduction: Osteoarthritis (OA) is a clinical condition affecting over 27 million Americans. There is no known cure for OA other than replacing the diseased joint with a joint prosthesis, total knee arthroplasty (TKA). Purpose: This study...
The vast knowledge of nucleic acids is evolving and it is now known that DNA can adopt highly complex, heterogeneous structures. Among the most intriguing are the G-quadruplex structures, which are thought to play a pivotal role in cancer...
This dissertation describes galvanic exchange of silver (Ag) nanostructures with PdCl42- in 1) various PdCl42- concentrations, 2) the presence of 0.1 M cetyitrimethylammonium bromide (CTAB), and 3) the presence of 0.1 M potassium bromide (KBr). It...
Historically in the area of pediatric heart failure, few options have been available that are specifically designed to provide pediatric circulatory support. Extracorporeal Membrane Oxygenation (ECMO) was the traditional method of choice, providing...
Health--Information resources; Health--Information services; Information networks
Background: Failure to achieve their goals of over 200 U.S. Health Information Exchange Networks (HIENs) which formed or operated in the U.S. from 2004 to 2010, lost time, capital and opportunity at individual, organizational and societal levels,...
The airline regulatory communities are interested in methods that can access degradation in the polymer insulation of aging aircraft wiring. This study investigates the response of bulk polymer films and aircraft wiring under indentation; changes...
Computer-aided minimally invasive surgery (MIS) has progressed significantly in the last decade and it has great potential in surgical planning and operations. To limit the damage to nearby healthy tissue, accurate modeling is required of the...
In some previous papers, feed forward configurations of realizing second order all pass transfer functions with complex poles by adding some configurations to a first order circuit are discussed. In this dissertation, the above idea extended to...
Advancements in medical therapy have augmented resources available to
physicians to treat disease and, because of this, spending on prescription drugs
has doubled in the past decade. Increasingly, clinical trials are demonstrating the
benefits of...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
United States. Army--History; Federal aid to law enforcement agencies--United States; Riots--United States
The function of the army of the United States is to protect the country against all enemies foreign and domestic. Everyone is cognizant of the accomplishments of the American forces against its foreign enemies; but there is another work, of equal...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is four pages and there is a large portion missing from the corner of each page.
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
The revolution in information technology and the explosion in the use of computing devices in people's everyday activities has forever changed the perspective of the data mining and machine learning fields. The enormous amounts of easily...
The main purpose of this research is to make a comparative study of the physical mechanisms related to highway noise barrier insertion loss and to evaluate and improve the accuracy of insertion loss of FHWA Traffic Noise Model (TNM) 2.5 comparedw...
Urbanization disrupts natural soil profiles and as watersheds are
urbanized, their surfaces become impervious and this will result in
reduction of infiltration. For this reason, many cities are facing problems
with treating runoff water. Best...
Web search engines; Automatic abstracting; Graph theory--Data processing
After a user types in a search query on a major search engine, they are presented with a number of search results. Each search result is made up of a title, brief text summary and a URL. It is then the user's job to select documents for...
Data Classification is a task that could be found in many life activities. In general, the term could be used for any activity that derives some decision or forecast based on the currently available information. Using a more accurate definition, a...
