Polymorphisms in the adrenergic receptor beta-2 (ADRB2) gene have been studied in relation to risk of Type 2 diabetes and obesity, but few studies have investigated associations with breast cancer. The purpose of this research was to evaluate the...
Because of limitations in randomized controlled trials, medical researchers are often forced to rely upon studies of observational data. Confounding is a major difficulty encountered in such studies that can create considerable bias in estimates of...
Contamination can be very difficult to remove from water. Once this water seeps into the ground, the difficulty grows exponentially. The Paducah Gaseous Diffusion Plant, located in Paducah, Kentucky, has contaminated the groundwater. The...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
Water treatment facilities strive to provide potable drinking water to the community which they service. The most common way of insuring drinkable water that is free of pathogens is water chlorination, but this can lead to the production of...
Determining the etiology of skeletal malocclusion is an important diagnostic step in treatment planning patients with maxillofacial anomalies. Aims: To describe cranial base morphology using cone beam computed tomography (CBCT) images and correlate...
Our research activities are based on the catalytic systems that provide resource-saving synthetic methodologies through gold-catalyzed reactions of alkynes and alkenes. We have worked on three applications: i) an effective and straightforward...
Enterprise zones--Kentucky--Louisville; Enterprise zones--Law and legislation; Regional planning--Kentucky--Louisville; Economic policy--Kentucky--Louisville
Multiple analytic methods are used to provide an
analysis and evaluation of specific economic and neighborhood
development policies undertaken by and continued by the
Commonwealth of Kentucky, the City of Louisville, and
Jefferson County since the...
Industrial management--Data processing; Supervision of employees--Data processing; Decision making--Data processing
This paper models a realistic problem involving workforce assignment and training for a large manufacturing environment. In this particular environment, the workforce is undertrained and most assignments will result in necessary training. This...
Simplified modeling generates a great deal of interest in the area of crashworthiness analysis. Modeling methods used to create simplified computer models for crashworthiness have been well developed. In advanced simplified models, researchers...
Blood flow--Measurement; Magnetic resonance imaging
Peripheral Arterial Disease (PAD) is a progressive atherosclerotic disorder which
is defined as any pathologic process obstructing the blood flow of the arteries supplying
the lower extremities. Moderate stenoses mayor may not be...
Indians of North America--Kentucky--Bullitt County--Antiquities; Excavations (Archaeology)--Kentucky--Ashworth Rockshelter site; Ashworth Rockshelter site (Ky.)
Reinvestigation of a National Register property, the Ashworth Rockshelter (15BU236), northeast of Shepardsville, Bullitt Co., Kentucky, revealed stratified Early Archaic through Mississippian components (ca. 7900 B.C.-1500 A.D.). Primary occupation...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
Xenoestrogens are spread throughout the environment affecting our daily
lives and may produce potential toxic effects on human health. The purpose of
this study was to develop a mechanistically reliable model capable of identifying
xenoestrogens....
Urinary incontinence is a major public health problem affecting 30% of community dwelling women aged 35-85. Urinary incontinence may have a significant impact on activities of daily living depending on the severity of symptoms. Women with urinary...
Graft rejection; Diagnostic imaging; Postoperative care
The fourth hand transplant recipient in Louisville lost his graft at nine months post transplant from ischemia due to severe graft arteriopathy. Conventional imaging techniques and clinical measurements, including CT angiography and measurements of...
The acetogenin annonacin, from the tropical annonaceous plant Annona muricata, is a lipophilic, mitochondrial complex I inhibitor reported to be more toxic than rotenone to mesencephalic neurons. The temperate annonaceous plant Asimina tri/oba...
Paramount Ballroom (Shanghai, China); Architecture--China--Shanghai; Buildings--China--Shanghai; Shanghai (China)--History--20th century; Shanghai (China)--Social life and customs--20th century
The Paramount Ballroom was an innovative urban space that challenged traditional
Chinese values. In doing so it played an important role in Shanghai's modernization.
Traditional Confucian morality set very strict regulations on the social...
Gold nanoparticles (AuNPs) have attracted enormous attention in the field of nanotechnology for applications such as, immunoassay, drug delivery, contrast enhancement and tumor therapy. The typical range of gold nanoparticles varies from 1– 150...
