This thesis begins by reviewing human N-acetyltransferases (Chapter I), then outlines experiments involving human hepatocytes and rat N-acetyltransferases (Chapters II-V). These experiments facilitated the development of a dissertation project...
Computer-assisted instruction; Three-dimensional imaging; Neuroanatomy--Study and teaching (Higher)
Visualizations in the form of computer-based learning environments are highly
encouraged in science education, especially for teaching spatial material. Some spatial
material, such as sectional neuroanatomy, is very challenging to learn. It...
A connected matching in a graph is a set of disjoint edges such that, for any pair of these edges, there is another edge of the graph incident to both of them. This dissertation investigates two problems related to finding large connected matchings...
Unrepaired DNA damage poses a serious threat to the genetic stability of a replicating cell. One mechanism of tolerating this damage is translesion DNA synthesis (TLS), in which an accessory polymerase synthesizes DNA directly across from a damaged...
III-nitrides (InN, GaN, AlN) are some of the most promising materials for making blue light emitting diodes (LED), blue laser diodes (LD) and high power, high temperature field effect transistors (FET). Current techniques produce GaN films with...
Longitudinal studies occupy an important role in scientific researches and clinical trials. When taking the analysis of longitudinal data, investigators are often confronted with missing data which will produce potential biases, even in...
Blood flow--Measurement; Magnetic resonance imaging
Peripheral Arterial Disease (PAD) is a progressive atherosclerotic disorder which
is defined as any pathologic process obstructing the blood flow of the arteries supplying
the lower extremities. Moderate stenoses mayor may not be...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 46. but is actually Vol. 18. No. 52. Pages seven and eight of this issue are missing.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 18. No. 51. but is actually Vol. 18. No. 55.
Potential dental implant site assessment is initially determined clinically. Subsequent radiographic assessment also provides information about the quantity of available bone. It was hypothesized that the use of radiographic markers in mandibular...
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
In 2003, Wilson Creek running through Bernheim Arboretum and Research Forest in central Kentucky was restored to its original winding path through a valley field. Early 20th century settlers had previously redirected this creek to run a straight...
Historically in the area of pediatric heart failure, few options have been available that are specifically designed to provide pediatric circulatory support. Extracorporeal Membrane Oxygenation (ECMO) was the traditional method of choice, providing...
Optimal trajectory generation is an essential part for robotic explorers to execute the total exploration of deep oceans or outer space planets while curiosity of human and technology advancements of society both require robots to search for...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue and pages one and pages one and six are very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. A quarter of the first two pages of this issue is missing as well as significant other portions. The following six pages...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 17. No. 42. but is actually Vol. 17. No. 49. There are significant portions missing along the edges...
