The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
The acetogenin annonacin, from the tropical annonaceous plant Annona muricata, is a lipophilic, mitochondrial complex I inhibitor reported to be more toxic than rotenone to mesencephalic neurons. The temperate annonaceous plant Asimina tri/oba...
This thesis reports the reactivity of the rhenium-thiolate complex, tris(2-diphenylphosphinobenzenethiolato)rhenium(III), [Re(DPPBT) 3 ] ( 1 ) and its oxidized derivatives with ethylene. The reactivity has been studied by electrochemical,...
Nitrile hydratase (NHase) is a metalloenzyme that contains a non-heme iron (III)
or non-corin cobalt (III) in a non-redox active role. NHase is used as biocatalyst in the
industry for the hydrolysis of nitriles to arnides. The trivalent metal ions...
The clinical experience represents a critical component in nursing education. During the clinical, students apply classroom theory to nursing practice and become socialized into the nursing profession. Because of the current nursing shortage,...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Pages three and four are missing from this issue and a large portion of pages seven and eight is missing.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue and pages one and three are very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a significant tear down the center of each page of this issue and pages one, three, six, and eight are very...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue and portions of page one are faded and all of page three is...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 15. No. 15. but is actually Vol. 15. No. 16. A small portion has been torn off along the bottom of...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 17. No. 18. but is actually Vol. 17. No. 19. The first page is very faded and there are portions...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There is a tear down the center of each page of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 30. No. 45. but is actually Vol. 30. No. 46. This issue is four pages and there is a crease across...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 14. but is actually Vol. 33. No. 17. There are creases across the center of each page that...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 3. No. 32. but is actually No. 33.