Integration; African Americans; Hospitals; Red Cross Hospital (Louisville, Ky.)
D.W. Beard was interviewed on November 29, 1979 about the Red Cross (Community) Hospital. He was a member of the board of Community Hospital, which was known previously as Red Cross Hospital. He discusses public perception of the hospital and the...
Medical education; Medical students; Kentucky School of Medicine
Catalog for the Kentucky School of Medicine for 1884. Includes list of board of regents and faculty, program information, matriculates 1883, graduation information, graduates of the Kentucky School of Medicine from 1851-1883. Incomplete catalog....
Computer-assisted instruction; Three-dimensional imaging; Neuroanatomy--Study and teaching (Higher)
Visualizations in the form of computer-based learning environments are highly
encouraged in science education, especially for teaching spatial material. Some spatial
material, such as sectional neuroanatomy, is very challenging to learn. It...
T cells; Disease susceptibility; Lupus; Sex factors in disease
Females are more susceptible to autoimmune disease than males. In several mouse models of disease, castration of males exacerbates disease while androgen treatment ameliorates disease. These data suggest hormones can have an influence on disease...
Tobacco smoke is a strong and independent risk factor for several chronic systemic diseases and also increases susceptibility to a multitude of bacterial infections, including periodontal infections. Periodontitis is a chronic inflammatory disease...
Inflammation is now recognized as an important factor in several age-related diseases such as arthritis, atherosclerosis, multiple sclerosis and diabetes. In each case, sub-clinical chronic inflammation occurs over years and leads to progressive...
Monophosphoryl Lipid A (MPLA), a derivative of LPS endotoxin, is a TLR4 agonist that displays as little as 0.1-1% as much toxicity as its parent molecule while retaining immunostimulatory properties. We discovered that MPLA activates a TRIF-biased...
Ligaments--Wounds and injuries; Knee--Wounds and injuries; Women athletes--Wounds and injuries
Anterior Cruciate Ligament (ACL) injuries are among the most common injuries incurred by both recreational and professional athletes. ACL injuries often occur during popular contact sports like basketball, football, volleyball and baseball, and...
Hip hop; Rap (Music); Alternative rock music; Geeks (Computer enthusiasts); Indie culture
In his documentary entitled, Nerdcore For Life, director Dan Lamoureux described Nerdcore as a "powerful social collision between hip hop and geek culture". Born on the Internet, Nerdcore Hip-Hop is rap music made by geeks, for geeks and...
In the retina, the receptive fields (RFs) of most neurons are comprised of an excitatory center and a suppressive surround. Retinal ganglion cell (RGC) RF center excitatory input arises from bipolar cell (BC) inputs, while their surround arises...
It has been estimated that 30% of all cancer deaths in the U.S. are associated with obesity. It is well-established that obesity promotes low-grade chronic inflammation, however the mechanisms by which obesity-induced chronic inflammation may...
The following thesis examines the relationship between site geology and ground motion amplification for medium sized earthquake events in the Ohio Valley area. This thesis also includes a Rapid Screening Guide that can be used to estimate...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
Ground-level ozone forecast models were developed for the following middle and small metropolitan areas in Kentucky: Ashland, Bowling Green, Owensboro, and Paducah. These models were nonlinear regression models, based on models previously developed...
Undertakers and undertaking; Business people; African American businesspeople; Politicians; African American politicians; Discrimination in public accommodations; Segregation--Law and legislation; Discrimination in employment; African...
Oral history interview with Goldie Winstead Beckett, conducted on September 12, 1978 by Ken Chumbley. In this interview, Mrs. Beckett discusses her life as well as her husband’s experiences as alderman in the city of Louisville in the late 1940s...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is four pages and there is a tear along the side of pages three and four.
Engine car of a train on a set of railroad tracks. The corner of a building is in the background. The front of the train has the numbers '60' on it. Handwritten on back: Old Oak Common. In pen: King Edward IV.
This dissertation is a hypothesis-driven research oriented study to determine the role of the pituitary-tumor transforming gene (PTTG) in ovarian cancer, specifically if it is involved in neoplastic transformation leading to tumorigenesis through...
Activity-based rehabilitation is important for clinically treating spinal cord injury (SCI). Advances in SCI research are dependent on quality animal models, which rely on our ability to detect functional differences in animals following injury....