Introduction: Autism is a complex developmental disability that typically appears during
the first three years of life, and is the result of a neurological disorder that affects the
normal functioning of the brain, impacting development in the...
Monoclonal antibodies directed toward tumor associated antigens are FDA approved anticancer reagents used commonly in the clinic. Administered antibodies initiate tumor cell death through several mechanisms. Improving immune mediated mechanisms,...
The properties of gold nanoparticles (GNP) holds promising potential for drug delivery, diagnostics, plasmonic photothermal therapy of diseases, electronics, catalysis, and photovoltaics (Liu et al., 2006; Huang et al., 2003; Thompson, 2007;...
DNA microarrays--Statistical methods; Gene expression--Statistical methods
Data derived from gene expression microarrays are frequently used to identify candidate genes which can characterize and distinguish between two biological phenotypes. A key step in this process is the selection of an appropriate test statistic to...
Crossover design is a type of longitudinal study with each subject receiving different treatments in different time periods. It has been used frequently in the pharmaceutical industry and other medical fields to investigate the safety and efficacy...
Athletic shoes; Foot--Wounds and injuries--Prevention
The purpose of this investigation was to determine if cycling shoes made with stiff material cause an increase in peak plantar stress over shoes with less stiff material. Shoe stiffness measurements were collected under controlled conditions and in...
Alcohol; Distillation; Alcoholic beverages; Corn--Utilization; Whiskey industry
In the whisky industry there is a balance between the desire to adhere to the traditional production process and the desire to increase profit margins. One solution that follows both stipulations is to increase the alcohol yield of a given batch of...
Rising concerns about dependency on fossil fuels in the 21st century has sparked a growth in research for renewable energy sources. One renewable energy production process of interest is the reduction of cellulose into fermentable sugars by means...
Electroencephalography; Visual evoked response; Drug addicts--Research
In 2006 it was estimated by the Substance Abuse and Mental Health Service Administration (SAMHSA, 2007) that 19.9 million Americans used illicit drugs, computing to roughly 8.0 % of the United States population. In 2007, there were 2.1 million...
In this dissertation research, we aim to solve problems of two types of survival data, clustered survival data with potentially informative cluster size and sojourn time data. The methods for these two types of data are different. However, both...
College graduates--Relocation; Educational attainment; Migration, Internal--United States
As state policymakers draw clearer connections between the college-level attainment of their residents and the corresponding economic and social benefits, there is great need for more data and information regarding the production and migration of...
Healthy Hoops Kentucky; Asthma in children--Social aspects; Asthmatics--Social conditions
Asthma is the most common chronic disease among children aged 7 to 17 years of age in the United States. An average, one of every ten school-aged children has asthma, and 13 million school days are missed each year due to asthma. Interventions to...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Several technical and economic obstacles currently hamper the industrial development of ethanol from biomass. One of the key bottlenecks is the slow kinetics of the enzymatic hydrolysis of cellulose, and the subsequent rate reduction as the...
This thesis is a methodological analysis of fire locations in Canadian provinces
from 2001 to 2010. The research presented in this thesis highlights the dominant fire
types for each province. Accurately locating active fires and burned area is...
The rate of overqualification, defined as a person having more education or skills than
their job requires them to have, has continued to grow since the issue was first identified
as a significant problem. Though evidence that suggests the rate of...
This dissertation is composed of three essays in which I examine the influence of formal institutions on entrepreneurs and new firms. In the first essay, "The Influence of Institutions on the Likelihood of Self-Employment: A Multilevel...
Introduction: The study investigated dimensional relationships between the sphenoid and maxillary sinuses and other selected craniomaxillofacial structures by using traditional cephalometric and volumetric procedures based on cone beam computed...
The theory of effectuation is ascending in entrepreneurship education. Hundreds of articles have been written on the topic. Many textbooks mention the theory, and one college level textbook teaches entrepreneurship entirely from an effectual...
Objective . To compare the in vitro reliability and accuracy of linear measurements between cephalometric landmarks on CBCT 3D images with varying basis projection images to direct measurements on human skulls. Methods . Sixteen linear dimensions...
