Hepatitis C virus--Research; Interferon--Therapeutic use; Adenosylmethionine
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease in the United States and is a huge burden on the US healthcare system. The FDA-approved traditional standard of care for HCV is pegylated interferon-alpha (lFNα) combined...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Page one of this issue is very faded and an advertisement has been clipped from the center of pages five and six.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This should be Vol. 12. but the masthead was set back to Vol. 10. earlier in the year and the mistake was never corrected.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 21. but is actually Vol. 33. No. 27. Page five is very faded.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 17. No. 33. but is actually Vol. 17. No. 39. This issue is twelve pages. There are illegible...
The lipid aldehydes, 4-hydroxy-2-nonenal (4-HNE) and propene-2-al (acrolein) are reactive α,β-unsaturated aldehydes generated during the peroxidation of lipids and are implicated in the pathogenesis of several oxidative-stress mediated diseases,...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 30. No. 41. but is actually Vol. 30. No. 42. This issue is four pages and there is a crease across...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Pages seven and eight of this issue are very faded.
The advent of larger storage spaces, affordable digital capturing devices, and an ever growing online community dedicated to sharing images has created a great need for efficient analysis methods. In fact, analyzing images for the purpose of...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
We formulate an integro-difference model to predict the growth and spatial
spread of a perennial plant population with an age-structured seed bank. We allow
the seeds in the bank to be of any age, producing an infinite system of equations.
The...
The airline regulatory communities are interested in methods that can access degradation in the polymer insulation of aging aircraft wiring. This study investigates the response of bulk polymer films and aircraft wiring under indentation; changes...
Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. Page one of this issue is very faded.
Alcoholic liver disease (ALD) is a serious concern for the world's population. It is one of the leading causes of death and is also a huge economic burden. The biochemical mechanisms responsible for ALD are incompletely understood, therefore there...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue should be Vol. 16. No. 34. but the masthead was set incorrectly and the mistake was never accounted for.