Economic development--Political aspects; Metropolitan areas--Economic aspects; Municipal government
Fragmentation of governments and urban sprawl has been a subject of debate for a considerable time. The discussion often centers on whether space (sprawl) and politics (fragmentation) make a difference in the economic development of metropolitan...
Neef, Joseph, 1770-1854; Pestalozzi, Johann Heinrich, 1746-1827
In the early nineteenth century the Pestalossian system of education became very popular in Europe, and, aided by the necessity of something positive to take the place of the decayed and formalistic systems then prevalent, the movement spread...
The classification of self-dual codes has been an extremely active area in
coding theory since 1972 [33]. A particularly interesting class of self-dual codes
is those of Type II which have high minimum distance (called extremal or...
Understanding the nucleation and early stage growth of crystals from the vapor phase is important for realizing large-area single-crystal quality films, controlled synthesis of nanocrystals, and the possible discovery of new phases of materials....
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Influenza--United States--Management; Epidemics--Management; Health services administration; Mathematical optimization
Pandemic influenza has been an important public health concern. During the 20th century, three major pandemics of influenza occurred in 1918, 1957, and 1968. The pandemic of 1918 caused 40 to 50 million deaths worldwide and more than 500,000 deaths...
Rapid Electrokinetic Patterning (REP) is a relatively new method for collecting and manipulating micrometer-scale particles at an electrode surface. REP is an AC electrokinetic technique that uses induced fluid motion to capture and manipulate...
High solids processing of biomass slurries provides the following benefits: maximized product concentration in the fermentable sugar stream, reduced water usage, and reduced reactor size. However, high solids processing poses mixing and heat...
Respiratory syncytial virus is the leading cause of lower respiratory tract infection
in infants and currently lacks an effective vaccine or treatment beyond symptom relief.
The atomic force microscope is particularly well suited for imaging...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are small portions missing along the edges of each page of this issue. This issue is twelve pages and is made up of...
The vast knowledge of nucleic acids is evolving and it is now known that DNA can adopt highly complex, heterogeneous structures. Among the most intriguing are the G-quadruplex structures, which are thought to play a pivotal role in cancer...
Wolf, Hugo, 1860-1903; Music and literature; Goethe, Johann Wolfgang von, 1749-1832. West-östlicher Divan; Ḥāfiẓ, 14th cent.
Johann Wolfgang von Goethe's West-ostlicher Divan combines the Persian influence of the fourteenth-century poet Hafiz with Goethe's own Germanic literary heritage. The result was a synthesis of symbolism and multivalent meanings that Goethe himself...
Integrins are major receptors for cell adhesion to the extracellular matrix, and play key roles in various cellular processes including adhesion, migration, proliferation and survival. Apart from developmental and physiological events, integrins...
Standard regularity assumptions for regression models are not satisfied in segmented regression models with an unknown change point, and consequently standard asymptotic results and inferential methods for confidence estimation are not applicable....
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
A new procedure has been developed for determining
the location of the source of certain EEG discharges
given the measured surface potentials. The
source is modeled as a single current dipole with arbitrary
position and orientation, while the head...
Metastasis is a complex process requiring directed migration of metastatic cells to favorable microenvironments. Increased CXCR4 expression has been implicated in more invasive, aggressive and metastatic tumor phenotypes and poor patient survival...
Computer arithmetic; Computer arithmetic and logic units; Computer algorithms
This research evaluates an innovative binary adder design and compares it against five standard adder designs. It begins with an algorithmic description of the five standard designs followed by the innovative design. It uses two metrics, speed and...
A growing interest has manifested itself within the past two or three years in "phytin" and "phytic acid", and in some of the compounds of the latter. Posternak first isolated this substance from the seeds of the red fir,...
Shakespeare, William, 1564-1616; Courtly love in literature
"It is in the south of France and at a very early period that we must look for the origin of the system of Courtly Love. Gathered about several small courts, there existed, as early as the eleventh century, a brilliant society, in which woman...
