The airline regulatory communities are interested in methods that can access degradation in the polymer insulation of aging aircraft wiring. This study investigates the response of bulk polymer films and aircraft wiring under indentation; changes...
Activity-based rehabilitation is important for clinically treating spinal cord injury (SCI). Advances in SCI research are dependent on quality animal models, which rely on our ability to detect functional differences in animals following injury....
This project investigated the effect of hypothermia on the monocyte response with the goal of understanding, which intracellular processes are affected by hypothermia leading to differences in cytokine secretion. A better understanding of the...
This work presents a novel comprehensive effort to understand the fluid dynamics within orbiting dishes and the effects of the resulting oscillating fluid flow on shear and endothelial cellular responses within the dishes. It is well documented...
Children with visual disabilities--Services for--Kentucky; Children with visual disabilities--Education--Kentucky; Self-help devices for people with disabilities--Kentucky; Students with disabilities--Services for--Kentucky
Assistive technology (AT) helps make the curriculum accessible to students with visual impairments. Studies have shown that half of these students are using assistive technologies. The purpose of this study was to seek a better understanding of the...
The area of total coloring is a more recent and less studied area than vertex and edge coloring, but recently, some attention has been given to the Total Coloring Conjecture, which states that each graph's total chromatic number xT is no greater...
Kentucky--History--Civil War, 1861-1865; United States--History--Civil War, 1861-1865
In the early days of 1861, Kentucky, torn between her allegiance to the federal government and her sympathy for the South, with her citizenry so divided that hardly a family in the state stood united, vainly endeavored to carve out for herself a...
The performance of pediatric circulatory support devices depends on the properties of pediatric blood. This study reports the measurement of the viscoelastic properties of pediatric blood at 37°C [body temperature]. The results were compared with...
The research problem presented herein involved the
structural determination of several a,~-unsaturated acids
and esters. The solution to this problem was sought in the
nuclear magnetic resonance (n.m.r.) spectra of these compounds.
The n.m.r....
Ten algal isolates were obtained from soil into axenic culture and placed into defined media containing from 0 to 50 ppm of DDT, 2, 4-D,2,4,5-T, rotenone, or malathion (in two purities, 95 and 99%). For nine of the isolates, growth was measured...
Knee--Mechanical properties; Knee--Pathophysiology; Gait in humans; Osteoarthritis
Osteoarthritis (OA) of the knee is associated with decline in functional capacity and ultimately leads to Total Knee Arthroplasty (TKA) in many of these patients. Exercise regimens prior to surgery may potentially enhance pre and post TKA...
Nanoparticles are a class of materials that exhibit unique physical and chemical properties compared to those of the same material at the bulk scale. One method of enhancing the thermal conductivity, and hence the heat transfer coefficient, of a...
Historically in the area of pediatric heart failure, few options have been available that are specifically designed to provide pediatric circulatory support. Extracorporeal Membrane Oxygenation (ECMO) was the traditional method of choice, providing...
Liquid gallium (Ga) spontaneously alloys with thin films of metals such as Ag, Au, Pt Al, and Cu at near or even below room temperature resulting in rapid self-assembly of nanostructures. In this dissertation, studies of the formation of these...
This dissertation focuses on the mechanisms and implications of perceptual learning of binocular interactions. Perceptual learning is an important means of adapting to the changing environment, demonstrating the possibility of neural plasticity in...
Aims. The primary aims of this randomized, controlled, blinded clinical trial were to
compare the hard and soft tissue response following either a connective tissue (CT) or
acellular dermal matrix (ADM) graft placed...
Arsenic--Physiological effect; Cardiovascular system--Diseases; Liver--Effect of arsenic on; Arsenic--Toxicology
Chronic arsenic exposure is associated with increased cardiovascular disease (CVD). Prenatal arsenic exposure at 49 ppm arsenic accelerates atherosclerosis underlying CVD in ApoE-/- mice, but the mechanism is unknown. This dissertation examines the...
Determining the mechanical properties of the spine is a significant step in understanding the behavior of the spine under normal conditions. Although a limited amount of data for cyclic loading is currently available, the tests are not completely...
The chaperone heat shock protein 90 (Hsp90) regulates physiologically and
pathological cellular processes, by binding and stabilizing kinases involved in basal
cellular functions and in cellular responses to stress, respectively. I hypothesize...
Nanoparticles; Imaging systems in medicine; Imaging systems in biology
Gold nanoparticles (GNPs) have shown beneficial properties for biomedical use, e.g., their non-toxic nature and surface properties for easy modification. Upon receiving light, they generate a strong surface plasmon field, which can alter the...