Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
Clustered longitudinal data is often collected as repeated measurements on subjects over time arising in the clusters. Examples include longitudinal community intervention studies, or family studies with repeated measures on each member. Meanwhile,...
INTRODUCTION: Attention Deficit/Hyperactivity Disorder (ADHD) is a disorder that is prevalent throughout the world. It is believed that 5% of school aged children suffer from ADHD, with some estimates indicating as high as 10% may suffer from the...
Pancreatic beta cells are extremely vulnerable to destruction by Reactive Oxygen Species (ROS). In type 1 diabetes and islet transplantation ROS are thought to be involved in the loss of beta cells. To test the role of antioxidant in islet...
Longitudinal studies occupy an important role in scientific researches and clinical trials. When taking the analysis of longitudinal data, investigators are often confronted with missing data which will produce potential biases, even in...
Pancreatic islet transplantation is a very promising treatment for type I diabetes. Many clinical trials have failed due to early islet loss and immune rejection. Reactive oxygen species (ROS) have been demonstrated to be involved in graft damage...
Heart--Hypertrophy; Heart--Physiology; Sugar in the body; Metabolism; Diabetes--Research
Heart failure is recognized as a major cause of death among diabetics. In type I and II diabetes, glucose uptake, glycolysis and pyruvate oxidation are impaired, and fatty acid utilization increases. These alterations in metabolism contribute...
Images, Photographic--Databases; Image processing--Digital techniques; Data mining; Cluster analysis
The performance of content-based image retrieval systems has proved to be inherently constrained by the used low level features, and cannot give satisfactory results when the user's high level concepts cannot be expressed by low level features. In...
It has been shown that GSK3 β plays a critical role in the inflammation response by differentially regulating MyD88-dependent pro- and anti-inflammatory cytokines production in TLR4-stimulated innate immune cells. The work included in this...
Recent advances in high throughput methodologies offer researchers the ability to understand complex systems via high dimensional and multi-relational data. One example is the realm of molecular biology where disparate data (such as gene sequence,...
Industrial efficiency; Industrial management; New products--Economic aspects
In today's market customers are increasingly demanding a greater number of options in the products they purchase. Offering products in greater variety helps industries cater to a wider range of customers. However, at the same time, this product...
Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
Regression analysis is a statistical method used to relate a variable of interest, typically y (the dependent variable), to a set of independent variables, usually, X1, X2,...,Xn . The goal is to build a model that assists statisticians in...
Introduction: The study investigated dimensional relationships between the sphenoid and maxillary sinuses and other selected craniomaxillofacial structures by using traditional cephalometric and volumetric procedures based on cone beam computed...
Pituitary tumor transforming gene ( PTTG ), also known as securing, is a novel oncogene that is expressed at high levels in most of the tumors analyzed to date. Overexpression of PTTG in mouse fibroblast(NIH 3T3) cells increases cell proliferation,...
Mishaps in prenatal development can influence mammary gland development
and, ultimately, affect susceptibility to factors that cause breast cancer. This research was
based on the underlying hypothesis that maternal dietary composition during...
Twenty-six fossil assemblages of land and freshwater molluscs from the Pliocene to the present, were collected from locations near the town of Meade, Kansas, U.S.A. and were analyzed (along with the extant molluscan fauna of Meade County, Kansas)...
Calculators--Study and teaching (Middle school); Functions--Study and teaching (Middle school); Algebra--Graphic methods; Computer-assisted instruction
The purpose of this study was to determine the effect of TI-Nspire graphing calculator use on student achievement and on teacher behavior variables of planning, teaching, and assessing. This study investigated the teaching of functions by teachers...
Diabetic cardiomyopathy (DCM) is a common complication leading to accelerated cardiovascular failure in diabetic patients. Even though the exact mechanism(s) behind this disease still remain unclear, research from several laboratories including our...
Polymorphisms in the adrenergic receptor beta-2 (ADRB2) gene have been studied in relation to risk of Type 2 diabetes and obesity, but few studies have investigated associations with breast cancer. The purpose of this research was to evaluate the...
