The thesis deals with the political career of John Marshall Harlan prior to his appointment in 1877 as an associate justice of the United States Supreme Court. Throughout the majority of those twenty-three active years in Kentucky politics, Harlan...
Alcoholic liver disease (ALD) is a serious concern for the world's population. It is one of the leading causes of death and is also a huge economic burden. The biochemical mechanisms responsible for ALD are incompletely understood, therefore there...
Oral history interview conducted with Nelson Goodwin on January 10, 1979 by Kenneth Chumbley. Mr. Goodwin, a nursery owner and local historian from Louisville, Kentucky, discusses his ancestors and other African Americans who lived in the...
Six sigma (Quality control standard); Manufacturing processes--Quality control--Statistical methods
The objective of this thesis was to apply what was learned from Six Sigma while working for General Electric, towards real applications to improve processes. Two manufacturing problems were targeted. One of the issues dealt with variation, in an...
Intelligent transportation systems; Air quality; Air--Pollution
Environmental or air quality impacts of Intelligent Transportation Systems (ITS)
are very difficult to measure. Some researchers have attempted to quantify the effects of
individual ITS application on emissions; yet, the effects of ITS as a whole...
Research over the past twenty five years has led to the development of the hypothesis that colorectal cancer is caused by the accumulation of mutations in tumor suppressor genes and proto-oncogenes. The last ten years has also revealed that the...
Bcl-2 proteins are major regulators of cellular responses to various apoptotic stimuli. Among them, overexpression of the anti-apoptotic BcI-2 protein BcI-xL modulates organelle-specific apoptotic pathways. To understand the mechanisms by which...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
Persecution--England--History--16th century; Martyrdom--Christianity--England; Great Britain--History--Elizabeth, 1558-1603; Great Britain--History--Mary, 1553-1558
This thesis is a historical examination of the Marian and Elizabethan persecutions. Through the analysis of primary sources dating from the persecutions, the process of persecution in Reformation England is examined. This thesis uncovers the...
Professional ethics does not differ in its essential nature from general ethics; both are concerned with problems of human conduct. The difference between the two is a difference of scope but not of nature. The scope of general ethics is as broad...
United States. Army--History--Civil War, 1861-1865; Confederate States of America. Army; Soldiers--Kentucky--Psychology--History--19th century; Soldiers--Kentucky--Attitudes--History--19th century
Beginning with Bell Irvin Wiley's 1943 The Life of Johnny Reb: The Common Soldier of the Confederacy, historians have produced many works describing the motivations for soldiers to enlist and serve during the Civil War. However, because they often...
The following thesis examines the relationship between site geology and ground motion amplification for medium sized earthquake events in the Ohio Valley area. This thesis also includes a Rapid Screening Guide that can be used to estimate...
McClellan, George Brinton, 1826-1885; Generals--United States--History--19th century; United States--History--Civil War, 1861-1865
This thesis is an examination of the factors that impacted the rise and fall of the military career of General George McClellan during the initial stages of the Civil War. It works almost exclusively with primary sources to gain a better...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
Louisville (Ky.)--History; Louisville (Ky.)--Social conditions; Cities and towns--Kentucky--History; Louisville (Ky.)--Economic conditions; Cities and towns--Growth--History--19th century
This thesis is a historical examination of the perception of Louisville as a southern city. The work begins with a discussion regarding Louisville's historical ties with the North and its acceptance as either a western or northern city. The thesis...
African Americans; African American churches; African American single mothers ; African American teenage mothers; Nursing homes; Nursing home administrators; People's Baptist Church (Louisville, Ky.); Single mothers; Teenage marriage; Teenage...
Oral history interview conducted on May 9, 1979 with Frances Smith by Mary Bobo. Mrs. Smith, a former nursing home owner and administrator discusses her childhood in Russellville, Kentucky, moving to Louisville at age twelve to tend to an aunt,...
Due to of the rise in numbers of persons experiencing homelessness, communities are working to restrict access that homeless individuals have to public spaces. Many cities across the nation have criminalized aspects of homelessness in attempts to...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
Genes in folate metabolizing pathway are responsible for modulating key enzymes in folate metabolisms necessary for DNA synthesis and repair and influence DNA methylation. Irregularity in DNA methylation may modify tumor phenotype response to...
Parasites; Medical parasitology; Parasitic diseases
This thesis investigated infection dynamics of parasitic nematodes at both the population
and individual levels by exploring evolutionary and historical aspects of infection as well
as how host-parasite interactions influence virulence. In...
