MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
Parking garages--Automation; Parking garages--Design and construction
Automated vehicle storage/retrieval system (AVS/RS) technology is relatively new. It has been applied successfully in several European facilities in 1990s. AVS/RS is a flexible system that is a viable alternative to automated storage/retrieval...
Educational change--Kentucky--Grant County; Student adjustment; High school students; Middle school students
This study investigated the impact of articulation activities and the extent to which the Grant County Kentucky school district operated as a learning organization during the implementation of a research-based middle to high school student...
This dissertation deals with various imidazole compounds with emphasis on hydrogen bond interactions and weaker intermolecular forces. New amide functionalized polyimidazole metal binding pockets are able to form intramolecular six-membered...
Nanoparticles; Imaging systems in medicine; Imaging systems in biology
Gold nanoparticles (GNPs) have shown beneficial properties for biomedical use, e.g., their non-toxic nature and surface properties for easy modification. Upon receiving light, they generate a strong surface plasmon field, which can alter the...
The vaccinia virus complement control protein (VCP) is involved in the modulation of the host inflammatory response during vaccinia virus infection. It possesses the ability to inhibit both classical and alternative pathways of complement...
Dimorphism is a highly conserved process in fungi in which a transition between a unicellular, yeast-like growth form and either a unicellular or multicellular, filamentous growth form occurs in response to several different environmental cues. The...
Knee--Mechanical properties; Knee--Pathophysiology; Gait in humans; Osteoarthritis
Osteoarthritis (OA) of the knee is associated with decline in functional capacity and ultimately leads to Total Knee Arthroplasty (TKA) in many of these patients. Exercise regimens prior to surgery may potentially enhance pre and post TKA...
Given a metric space (K, d), the hyperspace of K is defined by H(K) = {F c K: F is compact, F ≠ 0}. H(K) is itself a metric space under the Hausdorff metric dH. Hyperspaces have been extensively studied by topologists since the 1970's, but the...
This thesis describes 1) the kinetics of vapor phase place exchange reactions on films of gold monolayer protected clusters (Au MPCs) to alter the functionality of the Au MPCs, 2) applications of the reaction for altering chemiresistive sensing...
This thesis is an examination of the viability of a low pH hydrogen peroxide scrubbing process for removing H 2 S acid gas present in typical biogas streams generated from dairy farm anaerobic digesters. Biogas ranges in composition based on the...
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most fatal, with a rising incidence in the US as a result of the increase in alcoholic liver disease and obesity. Current therapeutic strategies are...
Aims. The primary aim of this randomized, blinded, controlled clinical trial was to compare the percent root coverage obtained using a coronally positioned tunnel surgery plus an acellular dermal matrix allograft (ADM) with single tooth sling...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
Aim. The efficacy of ridge preservation procedures using grafting materials and barrier membranes has been well established in the literature. However, the loss of horizontal width even with the utilization of intrasocket only guided bone...
Herbig Ae stars are young stars usually surrounded by gas and dust in the form of a disk and are thought to evolve into planetary systems similar to our own. We present a multi-wavelength examination of the disk and environment of the Herbig Ae...
In studying qualitative chemistry, two things impress you. The one being, the systematic, inclusive and generally accepted tables for the detection and identification of the several metals; the other, the lack of any agreement as to the method of...
Adjustment (Psychology) in old age; Aging; Elderly poor; Nursing home patients
BACKGROUND: Current successful aging theory excludes individuals with disease or
disability, limits the potential for successful aging in minority and lower socioeconomic
populations, focuses on behavioral determinants of health rather than social...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol 7. No. 2. but is actually Vol. 7. No. 1.
In this dissertation, we study the performance evaluation of two automated warehouse material handling (MH) technologies - automated storage/retrieval system (AS/RS) and autonomous vehicle storage/retrieval system (AVS/RS). AS/RS is a traditional...