The research problem presented herein involved the
structural determination of several a,~-unsaturated acids
and esters. The solution to this problem was sought in the
nuclear magnetic resonance (n.m.r.) spectra of these compounds.
The n.m.r....
Human arylamine N-acetyltransferase (NAT) is a phase II cytosolic enzyme that occurs as two isozymes, NAT1 and NAT2. This family of polymorphic enzymes catalyzes the detoxification and/or activation of many aromatic and heterocyclic amine drugs and...
This thesis looks at the optimization of fluid flow and mass transfer using computational fluid dynamics (CFD) in a micro fluidic coulter counter. CFD will be used to solve equations of fluid flow and mass transfer to see how molecules within the...
In fulfillment of the thesis project requirement for the Master of Fine Arts Degree at the University of Louisville, I portrayed the multiple roles of Clytemnestra, Electra and Athena in Dr. Steve Schultz's translation of Aeschylus'...
Traditionally, fingerprint image acquisition was based on contact. However
the conventional touch-based fingerprint acquisition introduces some problems
such as distortions and deformations to the fingerprint image. The most recent
technology for...
In fulfillment of the thesis project requirement for the Master of Fine Arts Degree at the University of Louisville, I portrayed the role of Paulina in William Shakespeare's The Winter's Tale. The production was directed by Dennis Krausnick,...
Interactions between chemokines and their receptors are involved in organ- specific homing and propagation of metastatic breast cancer (BrCa) cells. BrCa cells express higher levels of CXCR4 and CXCR7 mRNA and cell surface protein, than normal...
QSOs, providing distant, luminous sources of radiation, provide a means to detect gas by absorption in the interstellar and intergalactic medium. Of particular interest to astronomers studying metal line systems in lines of sight to QSOs are the...
MicroRNAs (miRNAs) regulate gene expression at the post-transcriptional level by repressing translation or stimulating mRNA degradation. In this study, I tested the hypothesis that miRNAs are differentially expressed in antiestrogen-sensitive MCF-7...
Heart--Diseases--Diagnosis; Diagnostic imaging; Magnetic resonance imaging; Imaging systems in medicine
Many cardiac diseases, such as myocardial ischemia, secondary to coronary artery disease, may be identified and localized through the analysis of cardiac deformations. Early efforts for quantifying ventricular wall motion used surgical implantation...
Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
Wolf, Hugo, 1860-1903; Music and literature; Goethe, Johann Wolfgang von, 1749-1832. West-östlicher Divan; Ḥāfiẓ, 14th cent.
Johann Wolfgang von Goethe's West-ostlicher Divan combines the Persian influence of the fourteenth-century poet Hafiz with Goethe's own Germanic literary heritage. The result was a synthesis of symbolism and multivalent meanings that Goethe himself...
This thesis is a personal examination of the process of creating, developing and portraying the character of Dionysus in University of Louisville's 1996 production of Euripides' The Bacchae. It begins with an examination of my acting process prior...
The aim of the research is to determine if cone beam computerized tomography reconstructed panoramic radiography viewed in two different focal trough shapes, and three different focal trough widths changes the ability to identify high risk...
United Parcel Service; Aeronautics, Commercial--Freight--Data processing; Forecasting--Data processing
This thesis develops a forecasting model to predict six different volume measures on a weekly and daily basis for UPS-Supply Chain Solutions (UPS-SCS). The volume measures are used by UPS-SCS to develop business plans, operation plans, and staffing...
Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) catalyze the detoxification and/or activation of aromatic and heterocyclic amine carcinogens by two pathways. This metabolism reaction can lead to the detoxification by Nacetylation, or...
Multiple normalization methods have been proposed for the analysis of microRNA microarray expression profiles but there is no consensus method. One of the more robust methods, quantile normalization, is commonly used in transcript (mRNA) studies...
Acting; Shakespeare, William, 1564-1616--Characters--Richard III; Shakespeare, William, 1564-1616. King Richard III
This thesis is a culmination of process and real life experiences I used as an actor to reach the goal of performing the role of Shakespeare's Richard III. Not only do I discuss the process I used, but I discuss the choices I made in pursuing this...
Varnish and its use has been known since ancient times. Altho the knowledge of varnish has been attributed to the Japanese as early as 500-600 B.C., Tschirsch and A.D. Stevens say that the Japs did not possess this art originally, but that they...
Musical pitch--Data processing; Sound--Recording and reproducing--Digital techniques
Many mathematical formulas and algorithms exist to identify pitches formed by human voices, and this has continued to be popular in the fields of music and signal pro-cessing. Other systems and research perform real time pitch identification...
