Tobacco smoke is a strong and independent risk factor for several chronic systemic diseases and also increases susceptibility to a multitude of bacterial infections, including periodontal infections. Periodontitis is a chronic inflammatory disease...
Complement, an early recognition system of innate immunity that senses local tissue damage and infection, cross-talks with and regulates other signaling systems, including Toll-like receptor (TLR) pathways. In the context of periodontitis,...
Unrepaired DNA damage poses a serious threat to the genetic stability of a replicating cell. One mechanism of tolerating this damage is translesion DNA synthesis (TLS), in which an accessory polymerase synthesizes DNA directly across from a damaged...
Mixed-effects model is an efficient tool for analyzing longitudinal data. The random effects in mixed-effects model can be used to capture the correlations among repeated measurements within a subject. The time points are not fixed and all...
Periodontitis--Age factors; Natural immunity; Age factors in disease
Age-related alterations in innate immunity are poorly understood. The identification of those mechanisms, which are dysfunctional in old age, will shed light on potential therapeutic strategies for chronic inflammatory diseases prevalent in the...
Periodontitis--Treatment; Peptides--Therapeutic use
Periodontitis and its systemic sequelae remain a major public health problem and
developing a cost-efficient therapy will benefit healthcare worldwide. Adherence of
Porphyromonas gingivalis to Streptococcus gordonii facilitates colonization of the...
Parasites; Medical parasitology; Parasitic diseases
This thesis investigated infection dynamics of parasitic nematodes at both the population
and individual levels by exploring evolutionary and historical aspects of infection as well
as how host-parasite interactions influence virulence. In...
Chronic periodontitis is strongly associated with composition of the oral biofilm
occupying the gingival crevicular aspect of the tooth and its associated root. Some gram-negative,
"red complex" bacteria instigate periodontal bone loss in...
Online organizations are always in search for innovative marketing strategies to better satisfy their current website users and lure new ones. Thus, recently, many organizations have started to retain all transactions taking place on their website,...
Tallis, Thomas, ca. 1505-1585. Lamentations, no. 1; Tallis, Thomas, ca. 1505-1585. Lamentations, no. 2; Byrd, William, 1542 or 3-1623. De Lamentatione Hieremiae;
Movement through pitch space in the Common Practice Period is generally acknowledged as being structured on the fifth relation, whereas movement through the pitch space of the highly chromatic music of the nineteenth century is thought of as being...
Parking garages--Automation; Parking garages--Design and construction
Automated vehicle storage/retrieval system (AVS/RS) technology is relatively new. It has been applied successfully in several European facilities in 1990s. AVS/RS is a flexible system that is a viable alternative to automated storage/retrieval...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 16. No. 18. but is actually Vol. 16. No. 20. This issue is twelve pages. The four page Gravure...
The clinical experience represents a critical component in nursing education. During the clinical, students apply classroom theory to nursing practice and become socialized into the nursing profession. Because of the current nursing shortage,...
A process for fabricating PMOS transistors and test devices has been developed for educational purposes as part of a microfabrication undergraduate/graduate laboratory course at the University of Louisville. This is to help students from multiple...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. The first page of this issue is very faded and an article has been clipped from pages three and four.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. There are portions missing along the edges of each page of this issue.
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue marks the paper increasing each issue back up to twelve pages instead of eight. The first four pages of this...
