The Consumer and Industrial group of the General Electric Company (GE) allocates its shipping truckload to seventeen different trucking companies over 701 different routes from each of its nine terminals to 48 contiguous states. One of the...
Chapter 1 detailed the synthesis method of hydroxamate peptides derivatives of pentapeptide Ac-PHSXX\'-N-NH2 by solid phase hydroxamate peptide synthesis method. The glutamic acid/aspartic acid side chain was modified to hydroxamic acid by on resin...
Dehydroepiandrosterone (DHEA) is a C-19 adrenal steroid and the most abundant circulating hormone in humans. Since circulating levels decline in late adulthood, treatment of humans with DHEA has been suggested to have beneficial health effects....
Vicinal dithioethers and alkenyl thioethers were synthesized under environmentally
friendly conditions using alkyne and thiol in water. Alkynes were also used to develop a
multibond-fonning reaction that fonned cyclic ketones or ketoesters through...
Hyaluronan (HA) is a major structural component of the ocular vitreous humor
(VH) and lipids are essential building blocks of cell membranes. However, little is known
about their possible interactions. The VH is known to undergo liquefaction...
This dissertation describes research focused on the synthesis, polymerization and
applications of cationic aminooxy lipids. An efficient and convenient method was
developed to stabilize liposomes using 'click chemistry'. The 'click...
Chapter I . Seven novel head-to-tail cyclic pentapeptides and pseudopentapeptides containing the arginine-glycine-aspartic acid (RGD) tripeptide motif were synthesized. All of the peptides were constructed using solid phase peptide synthesis....
When Howard Manning wakes from a fainting spell to find himself hospitalized with a serious but correctable weakness in his heart, his refusal of treatment intimates a death wish that provokes consternation among the skilled medical professionals...
Green tea--Health aspects; Green tea--Therapeutic use; Polyphenols--Physiological effect; Drug delivery systems; Lungs--Cancer--Treatment
Green tea polyphenols (GTPs) are gaining increasing attention because of their potential anti-tumor effects. However, poor oral bioavailability limits their efficacy in vivo. In this dissertation, two hypotheses were tested: 1) GTPs administered...
Music teachers--Kentucky; Vocational guidance; School music--Instruction and study--Kentucky
This phenomenological study examines the experiences of current music teachers to determine what influences them to pursue a career teaching at the elementary level. Eight elementary music teachers from rural counties in Kentucky were interviewed...
Nanoparticles; Drug delivery devices; Gene therapy
The properties and broad applications of nano-magnetic colloids have generated much interest in recent years. Specially, Fe304 nanoparticles have attracted a great deal of attention since their magnetic properties can be used for hyperthermia...
Xenoestrogens are spread throughout the environment affecting our daily
lives and may produce potential toxic effects on human health. The purpose of
this study was to develop a mechanistically reliable model capable of identifying
xenoestrogens....
This dissertation describes (1) size-dependent electrochemical oxidation/stripping of gold and silver nanoparticles (NPs), (2) alloying of copper with gold nanoparticles at underpotential deposition potentials, (3) electrochemical characterization...
This thesis describes 1) the kinetics of vapor phase place exchange reactions on films of gold monolayer protected clusters (Au MPCs) to alter the functionality of the Au MPCs, 2) applications of the reaction for altering chemiresistive sensing...
This dissertation deals with various imidazole compounds with emphasis on hydrogen bond interactions and weaker intermolecular forces. New amide functionalized polyimidazole metal binding pockets are able to form intramolecular six-membered...
Politicians' spouses; Politicians; Political campaigns
Mrs. Helen (Dillon) Mazzoli discusses her childhood and upbringing, as well as her life with Congressman Romano (Ron) Mazzoli. She describes their campaigns for office, including her own role and the ways the campaigns changed over time. She talks...
African Americans; African Americans--Social conditions; African Americans--Education; Segregation in education; Race relations; Louisville Municipal College for Negroes (Louisville, Ky.); University of Louisville; Civil rights
Oral history interview with Mrs. Amelia Ray, conducted on August 25, 1978 by Kenneth Chumbley. Mrs. Ray discusses her early life and upbringing in Tennessee as well as her life in Louisville. Mrs. Ray moved to Louisville in 1934 and attended...
Our research activities are based on the catalytic systems that provide resource-saving synthetic methodologies through gold-catalyzed reactions of alkynes and alkenes. We have worked on three applications: i) an effective and straightforward...
The role of mothers, the constitution of families, and the power of their stories are the bedrock of my thesis, which is the first 90 pages of a novel entitled Playing House . In it, I hope to investigate the denotation and connotation of the words...
Long-term exposure to harmful carcinogens like benzo[a]pyrene (BaP) are linked to lung cancer. Benzo[a]pyrene diol epoxide (BPDE), the ultimate carcinogen produced by BaP bioactivation, is believed to play an important role in lung carcinogenesis....
