This study expands our efforts to make a new class of Pt (II) compounds analogous to cisplatin and its derivatives using sterically hindered ligands. Pt compounds in this series have been synthesized using specially designed pyridine and...
The use of fiber reinforced polymer materials (composite FRP materials) to
strengthen existing concrete structures continues to expand as our current infrastructure
ages. However, one of the concerns when using FRP systems in this manner is...
Cardiac mapping has become an important area of research for understanding the mechanisms responsible for cardiac arrhythmias and the associated diseases. Current technologies for measuring electrical potentials on the surface of the heart are...
Liquid gallium (Ga) spontaneously alloys with thin films of metals such as Ag, Au, Pt Al, and Cu at near or even below room temperature resulting in rapid self-assembly of nanostructures. In this dissertation, studies of the formation of these...
For persons with disabilities, access to transportation is necessary for integration into society. The Americans with Disabilities Act (ADA) has been instrumental in assuring transportation access to individuals with disabilities for purposes of...
Ford Motor Company; Business logistics--Management; Production management; Manufacturing processes; Organizational change
For many years the concept of Lean Manufacturing has been applied in automotive development as a tool to refine the manufacturing practices to the greatest efficiency possible through waste reduction. Continuous Improvement is a quality innovation...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Obesity in children; Obesity in adolescence; Orthodontics
The purpose of this study was to determine if obesity impacts craniofacial dimensions in adolescent and teenage subjects. Twenty-one cephalometric measurements were selected as a basis for comparison between normal weight, overweight and obese...
This dissertation describes galvanic exchange of silver (Ag) nanostructures with PdCl42- in 1) various PdCl42- concentrations, 2) the presence of 0.1 M cetyitrimethylammonium bromide (CTAB), and 3) the presence of 0.1 M potassium bromide (KBr). It...
In this work, micro fabrication techniques are explored not only to simplify the production of complex lab on-a-chip devices (LOC), but also micro fabrication will be utilized to create intelligent design features that will enhance an...
The research in this dissertation describes a simple electrochemical approach for fabricating nanoscale (metal/metal) or molecular (metal/polymer or self assembled monolayer (SAM)/metal) junctions. The fabrication involves metal deposition on one...
Purpose: To evaluate baseline and 3 different image enhancements for the detection of landmarks and overall perceived quality in photostimuable phosphor cephalograms. Methods: DenOptix images of 48 patients (plus 12 repeats) were presented randomly...
Myocardial infarction; Glucose--Metabolism; Mitochondrial DNA
Heart failure is a leading cause of morbidity and mortality in the USA. During the development of heart failure, many cardiac parameters change at the same time including fuel metabolism, oxidative stress and mitochondrial function. Each of these...
Cortical and tectal inputs to the caudal LPN in the rat were examined using anatomical and physiological techniques. Pyramidal cells in layer 6 of the visual cortex and wide-field vertical cells in the stratum opticum of the superior colliculus...
The role of the active site tyrosine residue in the Co-C5' bond activation in the
context of adenosylcobalamin-dependent mutases has been computationally
investigated. The density functional, complete active space self-consistent field
and quantum...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. A large portion from pages five and six is missing from this issue.
We study a sensor location problem that minimizes the total number of sensors to install at road intersections in a transportation network so that the traffic flows on the entire network are uniquely determined. We employ the concepts of hidden...
Railroads--Kentucky--History; Kentucky--History--Civil War, 1861-1865
In studying and teaching history, I have been convinced that the transportation facilities of a country have helped or hindered its political, industrial and commercial development. In this thesis, I have endeavored to show the value of the...
Understanding the nucleation and early stage growth of crystals from the vapor phase is important for realizing large-area single-crystal quality films, controlled synthesis of nanocrystals, and the possible discovery of new phases of materials....
