Six sigma (Quality control standard); Manufacturing processes--Quality control--Statistical methods
The objective of this thesis was to apply what was learned from Six Sigma while working for General Electric, towards real applications to improve processes. Two manufacturing problems were targeted. One of the issues dealt with variation, in an...
Drug resistance in microorganisms; Salmonella typhimurium
Salmonella enterica serovar Typhimurium is an enteric pathogen capable of infecting
a wide range of hosts. The manner in which this pathogen is able to interact with its
host is difficult to define, as is the case with most microbes. Through the...
Longitudinal studies occupy an important role in scientific researches and clinical trials. When taking the analysis of longitudinal data, investigators are often confronted with missing data which will produce potential biases, even in...
All terrain vehicles--Automatic control; Motor vehicles--Automatic control; Intelligent control systems
When tracked vehicles traverse terrain such as sand, soil, or even concrete,
they may encounter a variance in density or viscosity of the medium that the
vehicle is traveling along. When this happens, one track begins to move faster or
slower...
Introduction: Autism is a complex developmental disability that typically appears during
the first three years of life, and is the result of a neurological disorder that affects the
normal functioning of the brain, impacting development in the...
Human adult olfactory epithelium contains neural progenitors (hONPs) which replace damaged cellular components throughout life. Methods to isolate and expand the hONPs have been developed in our laboratory. In response to morphogens, the hONPs...
20S proteasome, essential component of protein degradation mechanism, is important to maintain homeostasis. Its malfunctions have been associated with several pathological conditions. This study presents an extensive study of murine cardiac 20S...
Understanding of the band structure of the new nano materials is essential to have a deeper insight into their optical and electrical properties. Along with the existing techniques used for characterization of nano-materials, it is also important...
Recent studies indicate post-translational deacetylation by members of the superfamily of histone deacetylase complexes (HDACs) is necessary for oligodendrocyte precursor cell (OPC) differentiation into mature oligodendrocytes (OLs). However, it...
N-acetyltransferase 1 (NAT1) is a phase II metabolic enzyme responsible for the biotransformation of aromatic and heterocyclic amine carcinogens such as 4-aminobiphenyl (ASP). NAT1 catalyzes N-acetylation of arylamines as well as the 0-acetylation...
Pancreatic beta cells are extremely vulnerable to the destruction of Reactive Oxygen Species (ROS). In both type 1 and type 2 diabetes ROS are involved in the loss of U+000DF-cells. We hypothesized that the deficiency in ROS detoxifying system of...
This dissertation is a hypothesis-driven research oriented study to determine the role of the pituitary-tumor transforming gene (PTTG) in ovarian cancer, specifically if it is involved in neoplastic transformation leading to tumorigenesis through...
Neurosphere forming cells (NSFCs) have been derived from cultures of adult olfactory neuroepithelium obtained from patients and cadavers in serum rich medium. These neural progenitors remain undifferentiated when maintained in serum rich medium but...
Nosocomial infections; Catheterization--Complications; Drug resistance in microorganisms
Catheters represent an essential part of the management of critically and chronically ill patients. However, their use is often plagued by catheter related blood stream infections (CRBSIs), which are associated with increased morbidity, hospital...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue says Vol. 32. No. 9. but is actually Vol. 33. No. 12. There are creases across the center of each page that...
School yearbooks; Schools; Students; University of Louisville--Students; Alumni & alumnae; University of Louisville--Alumni and alumnae; Student organizations; Universities & colleges; Medical students; Law students; Dental students;...
Yearbook published by the senior classes of the College of Liberal Arts, the Speed Scientific School and the School of Law of the University of Louisville, Louisville, Kentucky, 1931.
School yearbooks; Schools; Students; University of Louisville--Students; Alumni & alumnae; University of Louisville--Alumni and alumnae; Student organizations; Universities & colleges; Medical students; Law students; Dental students; Music...
Yearbook published by the University of Louisville, Louisville, Kentucky, 1951.
The pulvinar is the largest nucleus of the human dorsal thalamus and is affected in a variety of brain disorders, such as schizophrenia. The experiments described in this dissertation elucidate key features of tecto-pulvino-cortical pathways as a...
Ribosomal biogenesis failure may contribute to neurodegenerative diseases, while its excessive activation has been shown to drive tumor growth. As ribosomal production is initiated and regulated by the Pol1-mediated transcription of rRNA genes in...
This research was performed to establish the feasibility of using Direct Metal Deposition (DMD) technology to deposit nickel powder to a nickel substrate. The substrate is electrodeposited pure nickel, and the material to be deposited is Metco...