Phase II clinical trial are generally single arm trial where a homogeneity assumption is placed on the response. In practice, this assumption may be violated resulting in a heterogeneous response. This heterogeneous or overdispersed response can be...
Computer-assisted instruction; Three-dimensional imaging; Neuroanatomy--Study and teaching (Higher)
Visualizations in the form of computer-based learning environments are highly
encouraged in science education, especially for teaching spatial material. Some spatial
material, such as sectional neuroanatomy, is very challenging to learn. It...
This thesis is an examination of the viability of a low pH hydrogen peroxide scrubbing process for removing H 2 S acid gas present in typical biogas streams generated from dairy farm anaerobic digesters. Biogas ranges in composition based on the...
Neuropsychology; Motor ability; Eye-hand coordination
Two major theoretical models, Direct Mapping and Functional Equivalence, suggest that the observation of action and imagery of action, respectively, involve activation of similar motor related areas. Despite the wealth of evidence that supports...
Introduction: Children diagnosed with an Autism Spectrum Disorder (ASD) often lack the ability to recognize and properly respond to emotional stimuli. These emotional deficits are also observed in children with Attention-Deficit Hyperactivity...
The phase II clinical trial is a critical step in the drug development process. In the oncology setting, phase II studies typically evaluate one primary endpoint, which is efficacy. In practice, a binary measurement representing the response to the...
Speech intelligibility has been found to improve with prior exposure to a reverberant room environment. It is believed that perceptual mechanisms help maintain accurate speech perception under these adverse conditions. Potential factors underlying...
Ligaments--Wounds and injuries; Knee--Wounds and injuries; Women athletes--Wounds and injuries
Anterior Cruciate Ligament (ACL) injuries are among the most common injuries incurred by both recreational and professional athletes. ACL injuries often occur during popular contact sports like basketball, football, volleyball and baseball, and...
Modular hip implants are currently being used in total hip arthroplasty revision procedures because it is common to have little or no bone left in the proximal region of the femur and it is difficult to accurately size implants based off of...
Many conflicting reports have been given in the literature concerning the effect of various factors on the rate of reversal of figure and ground in reversible perspective.
Flugel (7, 8) suggested that changes in eye movement increased the number of...
Previous studies on the mechanistic induction of anti-tumor responses by IL-12 cytokine therapy have focused on the adaptive immune response, specifically the activation NK cells and T cells as the primary targets of IL-12 treatment. In contrast,...
Short-term memory; Memory--Effect of sound on; Memory--Effect of noise on; Speech
The Irrelevant Speech Effect (ISE) is a phenomenon in which the presentation of
auditory materials (typically speech) impairs the serial recall of visually presented
materials, either digits or letters. Although this effect has been replicated in a...
Alcohol; Distillation; Alcoholic beverages; Corn--Utilization; Whiskey industry
In the whisky industry there is a balance between the desire to adhere to the traditional production process and the desire to increase profit margins. One solution that follows both stipulations is to increase the alcohol yield of a given batch of...
Narrative causal understanding is related to a variety of school-related skills such as reading comprehension, and memory. Previous research shows a developmental trend in the ability to use and understand causal connections that begins at age 4...
Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with poor prognosis.
To address this disease broadly, the candidate engaged in clinical work, literature
analysis, database analysis, and laboratory work. The clinical work culminated...
This study investigates the placebo effect in randomized controlled trials of low back pain. This effect has not been analyzed over time or in respect to low back pain. A meta-analysis was performed using the Pubmed/Medline database for low back...
The game of Snake has been selected to provide a unique application of the
TD( ) algorithm as proposed by Sutton. A reinforcement learning technique for
producing computer controlled players is documented. Using value function
approximation with...
Menthol has been regularly utilized as a treatment in sports related injuries for many years, yet little is known about its physiological interactions or its effect on performance. Our previous study indicates that topically applied menthol may...
This work examines our perception of distance within "action space" (about 2m ~ 30m), an ability that is important for various actions. Two general problems are addressed: what information can be used to judge distance accurately and how...
Enzymatic hydrolysis is an important, but time limiting step in the process of converting biomass into ethanol. High solids concentrations are desired in order to minimize reactor size and achieve a higher concentration of glucose in the end...
