Recent studies indicate post-translational deacetylation by members of the superfamily of histone deacetylase complexes (HDACs) is necessary for oligodendrocyte precursor cell (OPC) differentiation into mature oligodendrocytes (OLs). However, it...
INTRODUCTION: Heart failure is a major and growing public health concern. Although heart failure has been considered an inexorable and progressive disorder, emerging evidence suggests that some patients may have reversible left ventricular...
Vascular injury and chronic arterial diseases such as atherosclerosis and restenosis result in exposure of vascular smooth muscle cells (VSMCs) to increased concentrations of growth factors triggering a change from a contractile to a synthetic...
The purpose of this study was to assess the effects of short-term high-intensity resistance training on time to exhaustion at maximal aerobic output. It was hypothesized that 2 weeks of training will induce improvements in performance at maximal...
Parasites; Medical parasitology; Parasitic diseases
This thesis investigated infection dynamics of parasitic nematodes at both the population
and individual levels by exploring evolutionary and historical aspects of infection as well
as how host-parasite interactions influence virulence. In...
Edgard Varese began composing "Deserts" in 1949 and completed it late in 1954. Scored for fifteen instruments, five percussionists and two tapes of organized sounds, "Deserts" comprises acoustic instrumental music and sections...
Parkinson's disease--Treatment; Stem cells--Therapeutic use
Parkinson's disease (PD) is a hypokinetic movement disorder resulting from the
progressive neurodegeneration of the dopaminergic nigrostriatal system in the brain and
the resulting imbalance between dopamine and acetylcholine in the basal ganglia...
Ethnocentrism; Mass media--Social aspects; Social problems--Press coverage; Mass media and public opinion; Mass media and race relations
This study revisits Kinder's and Kam's (2007; 2009) studies that provided
political scientists with a theoretical and operational definition of ethnocentrism-our
tendency to partition the world into in-groups and out-groups. They assert that...
Reperfusion of the ischemic lung causes pulmonary arteriolar vasoconstriction and reduces alveolar perfusion. Lung ischemia-reperfusion (IR) injury leads to platelet and leukocyte activation which could contribute to decreased alveolar perfusion...
The Louisville Leader was an African-American newspaper published from 1917 to 1950 by I. Willis Cole in Louisville, Kentucky. This issue is twelve pages. There are small portions missing along the top of each page of this issue. Almost half of...
Psychic trauma in art; Psychoanalysis and art; Art--Psychological aspects; Salomon, Charlotte, 1917-1943. Leben oder theater?
This thesis explores the presence of the dialectic of trauma in Charlotte Salomon’s magnum opus, Life? or Theatre?, a series of more than seven hundred paintings created during her time in exile in France between 1941 and 1942. In this series,...
Ligaments--Wounds and injuries; Knee--Wounds and injuries; Women athletes--Wounds and injuries
Anterior Cruciate Ligament (ACL) injuries are among the most common injuries incurred by both recreational and professional athletes. ACL injuries often occur during popular contact sports like basketball, football, volleyball and baseball, and...
Kentucky--History--1792-1865; United States--History--Civil War, 1861-1865--Causes
During the secession winter of 1860-61 the Commonwealth of Kentucky found itself caught in the middle of the great sectional controversy. With the Union's fate hanging in the balance Kentucky figured as a prominent player in the outcome of that...
Intonation (Musical pitch); Flute--Intonation; Singing--Intonation; Music--Instruction and study
The purpose of this study is to measure the effect of listening to and singing a tuning
pitch on a flute player's intonation. This investigation determines if these two
variables-hearing and singing-will have an effect on playing a single...
Shen, Fu, 1763-ca. 1808. Fu sheng liu ji; Shen, Fu, 1763-ca. 1808--Criticism and interpretation; Chinese literature--Qing dynasty, 1644-1912--History and criticism; Conduct of life in literature
This study endeavored to provide a new path to understand Fusheng liu
ji (Six Chapters of a Floating Life) by Shen Fu in the middle of the Qing
Dynasty (1636-1911). Shen Fu recorded his love story with his wife Chen Yun and his life as a Chinese...
Qubbat al-Sakhrah (Mosque : Jerusalem); Jerusalem--Buildings, structures, etc.; Abd al-Malik ibn Marwan, Caliph, 642-705
This thesis provides a hypothesis as to why the Dome of the Rock
was built. I examine various scholarly theories concerning the
construction of the first notable work of Islamic architecture, which was
built in Jerusalem during the last decade of...
Cynicism--Kentucky--Louisville; Public opinion--Kentucky--Louisville; Metropolitan government--Kentucky--Louisville
The government's ability to gain and hold a high proportion of citizens' trust is essential to the functioning of an efficient and successful administration at the federal, state, and local levels. This thesis is a quantitative study aimed at...
Anxiety in children; Anxiety--Physiological aspects
Anxiety disorders are prevalent in both adult and child populations, and are associated with significant economic and psychosocial costs. There are clearly familial patterns of transmission within the anxiety disorders, and the inherited risk is...
The inherited bone marrow failure syndromes (IBMFS) encompass a heterogeneous collection of rare disorders characterized by hematological abnormalities, generalized growth delays, and an increased incidence of malignant transformation. These...
This study focuses on the variation in structural response to synthetic ground motions derived from the latest attenuation models developed for the Central Eastern United States (CEUS) and used by the USGS to develop the latest edition (2008) of...